2-Oxazolidinone, 3-[(1R)-1-cyclohexyl-2-nitroethyl]-4-phenyl-, (4R)-

Base Information

Chemical Name:2-Oxazolidinone, 3-[(1R)-1-cyclohexyl-2-nitroethyl]-4-phenyl-, (4R)-
CAS No.:189350-21-8
Molecular Formula:C17H22N2O4
Molecular Weight:318.373
Hs Code.:
DSSTox Substance ID:DTXSID90445209
Nikkaji Number:J854.385B
Wikidata:Q82263562

Synonyms:189350-21-8;2-Oxazolidinone, 3-[(1R)-1-cyclohexyl-2-nitroethyl]-4-phenyl-, (4R)-;DTXSID90445209;(4R)-3-[(R)-1-Cyclohexyl-2-nitroethyl]-4-phenyloxazolidin-2-one

Suppliers and Price of 2-Oxazolidinone, 3-[(1R)-1-cyclohexyl-2-nitroethyl]-4-phenyl-, (4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Oxazolidinone, 3-[(1R)-1-cyclohexyl-2-nitroethyl]-4-phenyl-, (4R)-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:318.15795719
Heavy Atom Count:23
Complexity:425

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)C(C[N+](=O)[O-])N2C(COC2=O)C3=CC=CC=C3
Isomeric SMILES:C1CCC(CC1)[C@H](C[N+](=O)[O-])N2[C@@H](COC2=O)C3=CC=CC=C3

Technology Process of 2-Oxazolidinone, 3-[(1R)-1-cyclohexyl-2-nitroethyl]-4-phenyl-, (4R)-

There total 4 articles about 2-Oxazolidinone, 3-[(1R)-1-cyclohexyl-2-nitroethyl]-4-phenyl-, (4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 50598-92-0
2-cyclohexyl-1-nitroethene

: 90319-52-1,7480-32-2
(4R)-phenyl-2-oxazolidinone

: 189350-21-8
(R)-3-((R)-1-Cyclohexyl-2-nitro-ethyl)-4-phenyl-oxazolidin-2-one

Guidance literature:: (4R)-phenyl-2-oxazolidinone; With tetraethylammonium perchlorate; In various solvent(s); at 0 ℃; Electrochemical reaction;

2-cyclohexyl-1-nitroethene; In various solvent(s); at -78 ℃;
DOI:10.1016/S0957-4166(01)00385-8

Reference yield: 78.0%

: 50598-92-0,132839-80-6
(E)-(2-nitrovinyl)cyclohexane

: 90319-52-1,7480-32-2
(4R)-phenyl-2-oxazolidinone

: 189350-21-8
(R)-3-((R)-1-Cyclohexyl-2-nitro-ethyl)-4-phenyl-oxazolidin-2-one

Guidance literature:: (4R)-phenyl-2-oxazolidinone; With 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 1h;

(E)-(2-nitrovinyl)cyclohexane; In tetrahydrofuran; at -78 ℃; for 0.25h;

Reference yield:

: 141377-56-2,141434-99-3,149559-83-1,50598-90-8
1-cyclohexyl-2-nitroethanol

: 189350-21-8
(R)-3-((R)-1-Cyclohexyl-2-nitro-ethyl)-4-phenyl-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: dicyclohexylcarbodiimide; copper(I) chloride / diethyl ether / 12 h

2.1: potassium tert-butoxide; 18-crown-6 / tetrahydrofuran / 1 h / 0 °C

2.2: 78 percent / tetrahydrofuran / 0.25 h / -78 °C

With 18-crown-6 ether; potassium tert-butylate; dicyclohexyl-carbodiimide; copper(l) chloride; In tetrahydrofuran; diethyl ether; 1.1: Dehydration / 2.1: Metallation / 2.2: Addition;