5-Hydroxytryptoline

Base Information

• Chemical Name: 5-Hydroxytryptoline
• CAS No.: 23778-34-9
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.229
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID30178463
• Nikkaji Number: J53.905H
• Wikidata: Q27137401
• Mol file: 23778-34-9.mol

Synonyms:5-hydroxy-9H-1,2,3,4-tetrahydropyrido(3,4-b)indole;5-hydroxytryptoline;5-hydroxytryptoline monohydrochloride;6-hydroxytetrahydro-beta-carboline;6-hydroxytetrahydronornarmane;6-hydroxytryptoline

Chemical Property of 5-Hydroxytryptoline

Chemical Property:

• Vapor Pressure: 8.33E-08mmHg at 25°C
• Boiling Point: 424.5°Cat760mmHg
• Flash Point: 210.5°C
• PSA: 48.05000
• Density: 1.314g/cm³
• LogP: 1.84800
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 188.094963011
• Heavy Atom Count: 14
• Complexity: 221

Purity/Quality:

98%min ^*data from raw suppliers

2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOL-6-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNCC2=C1C3=C(N2)C=CC(=C3)O
• Description: The dried fruit of Plectocorniopsis gerninijZorus contain this carboline alkaloid to the extent of 0.07 per cent. It yields a crystalline hydrochloride and sulphate, both above 300°C; the acetate, m.p. 293-5°C, picrate, m.p. 240°C and the O,N_x0002_diacetyl derivative, m.p. l68-170°C. The assigned structure, based upon spectroscopic data, has been confirmed by demethylation of 6-methoxytetrahydro-(3- carboline to give the alkaloid.

Technology Process of 5-Hydroxytryptoline

There total 1 articles about 5-Hydroxytryptoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

N,N'-dimethylbenzylamine (103-83-3) + serotonin hydrochloride (153-98-0,21591-86-6) → 6-Hydroxytetrahydronorharmane (23778-34-9) + 3,4,5,6-tetrahydro-7-hydroxy-1H-azepino[5,4,3-cd]indole + 3,4,5,6-tetrahydro-7-hydroxy-6-phenyl-1H-azepino[5,4,3-cd]indole (374680-40-7)

Guidance literature:

With oxygen; In methanol; for 6h; Heating;

DOI:10.1248/cpb.49.1159

upstream raw materials:

N,N'-dimethylbenzylamine

serotonin hydrochloride