(20S)-Protopanaxadiol

Base Information

Chemical Name:(20S)-Protopanaxadiol
CAS No.:30636-90-9
Molecular Formula:C₃₀H₅₂O₃
Molecular Weight:460.741
Hs Code.:
UNII:MR8AEF5T1N
Nikkaji Number:J38.608A
Wikipedia:Protopanaxadiol
Wikidata:Q7252079
Metabolomics Workbench ID:133117
ChEMBL ID:CHEMBL375563
Mol file:30636-90-9.mol

Synonyms:20(S)-protopanaxadiol;dammar-24-ene-3beta, 6alpha, 12beta, 20-tetrol, (20s)-;protopanaxadiol;protopanaxadiol, (3beta,12beta)-isomer

Suppliers and Price of (20S)-Protopanaxadiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Protopanaxadiol
250mg
$ 1051.00

AK Scientific
Protopanaxadiol
1g
$ 2273.00

American Custom Chemicals Corporation
DAMMAR-24-ENE-3 BETA,12BETA,20-TRIOL 95.00%
5MG
$ 453.42

ApexBio Technology
Protopanaxdiol
20mg
$ 109.00

Arctom
(20S)-Protopanaxdiol ≥98%
20mg
$ 50.00

AvaChem
20(S)-Protopanaxadiol
10mg
$ 59.00

AvaChem
20(S)-Protopanaxadiol
25mg
$ 79.00

AvaChem
20(S)-Protopanaxadiol
100mg
$ 119.00

AvaChem
20(S)-Protopanaxadiol
5mg
$ 49.00

AvaChem
20(S)-Protopanaxadiol
250mg
$ 190.00

Total 84 raw suppliers

Chemical Property of (20S)-Protopanaxadiol

Chemical Property:

Vapor Pressure:7.57E-15mmHg at 25°C
Melting Point:197-200 °C
Boiling Point:559.5°Cat760mmHg
PKA:14.96±0.70(Predicted)
Flash Point:226.1°C
PSA：60.69000
Density:1.036
LogP:6.50060
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
XLogP3:7.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:460.39164552
Heavy Atom Count:33
Complexity:783

Purity/Quality:

95%-98% ^*data from raw suppliers

Protopanaxadiol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)O)C)C)O)C)O)C
Isomeric SMILES:CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)O)C)O)C
Uses (20S)-Protopanaxadiol is used in the treatment of cerebral ischemic injury and the reversal of oxidative stress. A novel class of AMP-activated protein kinase (AMPK) inhibitors affecting glucose and lipid metabolism.

Technology Process of (20S)-Protopanaxadiol

There total 10 articles about (20S)-Protopanaxadiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51116-90-6
12-β-O-hydroxy-20(S)-hydroxydammarane-24-ene-3-one

: 6892-79-1,7755-01-3,30636-90-9,38243-15-1,53368-76-6,103834-30-6
protopanaxadiol

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol;
DOI:10.1016/0008-6215(88)85045-6

Reference yield:

: 6892-79-1
(20S)-dammar-24-ene-3α,12β,20-triol

: 6892-79-1,7755-01-3,30636-90-9,38243-15-1,53368-76-6,103834-30-6
protopanaxadiol

Guidance literature:: Multi-step reaction with 2 steps

1: CrO₃; pyridine

2: NaBH₄ / propan-2-ol

With pyridine; chromium(VI) oxide; sodium tetrahydroborate; In isopropyl alcohol;
DOI:10.1007/s10600-006-0035-4