2-Pyridinecarbamic acid, 6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-, ethyl ester

Base Information

Chemical Name:2-Pyridinecarbamic acid, 6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-, ethyl ester
CAS No.:82585-86-2
Molecular Formula:C18H24N6O5
Molecular Weight:404.4204
Hs Code.:
NSC Number:91004

Synonyms:NSC91004;82585-86-2;SCHEMBL10749321;NSC-91004;2-Pyridinecarbamic acid, 6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-, ethyl ester;Carbamic acid, [6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-2-pyridinyl]-, ethyl ester;ethyl N-[6-amino-4-[[2-hydroxy-3-(N-methylanilino)propyl]amino]-5-nitro-2-pyridyl]carbamate

Suppliers and Price of 2-Pyridinecarbamic acid, 6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 2-Pyridinecarbamic acid, 6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-, ethyl ester

Chemical Property:

Vapor Pressure:5.99E-17mmHg at 25°C
Boiling Point:634.1°Cat760mmHg
Flash Point:337.3°C
Density:1.416g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:9
Exact Mass:404.18081789
Heavy Atom Count:29
Complexity:527

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=NC(=C(C(=C1)NCC(CN(C)C2=CC=CC=C2)O)[N+](=O)[O-])N

Technology Process of 2-Pyridinecarbamic acid, 6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-, ethyl ester

There total 3 articles about 2-Pyridinecarbamic acid, 6-amino-4-[[2-hydroxy-3-(methylphenylamino)propyl]amino]-5-nitro-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 63062-22-6
3-(N-Methyl-N-phenylamino)-2-hydroxypropylamine

: 6506-86-1
ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

: 82585-86-2
ethyl 6-amino-4-<<2-hydroxy-3-(N-methyl-N-phenylamino)propyl>amino>-5-nitro-2-pyridinecarbamate

Guidance literature:: With triethylamine; In methanol; at 60 ℃; for 18h;
DOI:10.1021/jm00351a008

Reference yield:

: 14236-04-5
N-methyl-N-(oxiran-2-ylmethyl)aniline

: 82585-86-2
ethyl 6-amino-4-<<2-hydroxy-3-(N-methyl-N-phenylamino)propyl>amino>-5-nitro-2-pyridinecarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: NH₃ / ethanol / 3 h / 100 °C

2: 73 percent / Et₃N / methanol / 18 h / 60 °C

With ammonia; triethylamine; In methanol; ethanol;
DOI:10.1021/jm00351a008

Reference yield:

: 100-61-8
N-methylaniline

: 82585-86-2
ethyl 6-amino-4-<<2-hydroxy-3-(N-methyl-N-phenylamino)propyl>amino>-5-nitro-2-pyridinecarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol; H₂O / 2 h / Heating

2: NH₃ / ethanol / 3 h / 100 °C

3: 73 percent / Et₃N / methanol / 18 h / 60 °C

With ammonia; triethylamine; In methanol; ethanol; water;
DOI:10.1021/jm00351a008