Butanoic acid, 3,3-dimethyl-2-[2-oxo-2-(phenylamino)ethyl]-, (R)-

Base Information

Chemical Name:Butanoic acid, 3,3-dimethyl-2-[2-oxo-2-(phenylamino)ethyl]-, (R)-
CAS No.:192202-67-8
Molecular Formula:C₁₄H₁₉NO₃
Molecular Weight:249.31
Hs Code.:
DSSTox Substance ID:DTXSID70445787
Wikidata:Q82264315
Mol file:192202-67-8.mol

Synonyms:Butanoic acid, 3,3-dimethyl-2-[2-oxo-2-(phenylamino)ethyl]-, (R)-;192202-67-8;DTXSID70445787

Suppliers and Price of Butanoic acid, 3,3-dimethyl-2-[2-oxo-2-(phenylamino)ethyl]-, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Butanoic acid, 3,3-dimethyl-2-[2-oxo-2-(phenylamino)ethyl]-, (R)-

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:249.13649347
Heavy Atom Count:18
Complexity:301

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(CC(=O)NC1=CC=CC=C1)C(=O)O
Isomeric SMILES:CC(C)(C)[C@@H](CC(=O)NC1=CC=CC=C1)C(=O)O

Technology Process of Butanoic acid, 3,3-dimethyl-2-[2-oxo-2-(phenylamino)ethyl]-, (R)-

There total 3 articles about Butanoic acid, 3,3-dimethyl-2-[2-oxo-2-(phenylamino)ethyl]-, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 117237-87-3
(R)-2-t-butylsuccinic anhydride

: 62-53-3
aniline

: 192202-67-8
(R)-3,3-Dimethyl-2-phenylcarbamoylmethyl-butyric acid

Guidance literature:: With pyridine; Ambient temperature;
DOI:10.1021/jm9606608

Reference yield:

: 59322-59-7
2-tert-butyl-butanedioic acid diethyl ester

: 192202-67-8
(R)-3,3-Dimethyl-2-phenylcarbamoylmethyl-butyric acid

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / conc. aq. HCl / Heating

3: 95 percent / Ac₂O / 5 h / 100 °C

4: 71 percent / pyridine / Ambient temperature

With pyridine; hydrogenchloride; acetic anhydride;
DOI:10.1021/jm9606608

Reference yield:

: 117237-95-3
(R)-2-t-butylsuccinic acid

: 192202-67-8
(R)-3,3-Dimethyl-2-phenylcarbamoylmethyl-butyric acid

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / Ac₂O / 5 h / 100 °C

2: 71 percent / pyridine / Ambient temperature

With pyridine; acetic anhydride;
DOI:10.1021/jm9606608