3-(4-Bromophenyl)-6-methoxybenzo[b]thiophene

Base Information

Chemical Name:3-(4-Bromophenyl)-6-methoxybenzo[b]thiophene
CAS No.:192443-25-7
Molecular Formula:C15H11BrOS
Molecular Weight:319.222
Hs Code.:
DSSTox Substance ID:DTXSID90572640
Nikkaji Number:J1.083.834G
Wikidata:Q82461060
Mol file:192443-25-7.mol

Synonyms:192443-25-7;3-(4-Bromophenyl)-6-methoxybenzo[b]thiophene;SCHEMBL5043116;DTXSID90572640;XQHVZCQNQQRWJL-UHFFFAOYSA-N;3-(4-Bromophenyl)-6-methoxy-1-benzothiophene;3-(4-Bromo-phenyl)-6-methoxy-benzo[b]thiophene

Suppliers and Price of 3-(4-Bromophenyl)-6-methoxybenzo[b]thiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-(4-Bromophenyl)-6-methoxybenzo[b]thiophene

Chemical Property:

XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:317.97140
Heavy Atom Count:18
Complexity:278

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=CS2)C3=CC=C(C=C3)Br

Technology Process of 3-(4-Bromophenyl)-6-methoxybenzo[b]thiophene

There total 10 articles about 3-(4-Bromophenyl)-6-methoxybenzo[b]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 225222-73-1
1-(4-bromophenyl)-2-(3-methoxyphenylsulfanyl)-ethanone

: 192443-25-7
3-(4-bromo-phenyl)-6-methoxy-benzo[b]thiophene

Guidance literature:: With aluminum (III) chloride; In dichloromethane; at 5 - 20 ℃;
DOI:10.1080/00397911.2019.1611856

Reference yield: 20.0%

: 192436-87-6
(4-bromophenyl)(4-methoxy-2-methylsulfanylphenyl)methanone

: 192443-25-7
3-(4-bromo-phenyl)-6-methoxy-benzo[b]thiophene

Guidance literature:: (4-bromophenyl)(4-methoxy-2-methylsulfanylphenyl)methanone; With potassium tert-butylate; In tetrahydrofuran; Heating;

With trifluoroacetic acid; In toluene; at 0 ℃; for 2h;
DOI:10.1021/jm021120f

Reference yield:

: 456-49-5
1-fluoro-3-methoxybenzene

: 192443-25-7
3-(4-bromo-phenyl)-6-methoxy-benzo[b]thiophene

Guidance literature:: Multi-step reaction with 3 steps

1.1: AlCl₃ / nitrobenzene / 0.17 h / 0 - 8 °C

1.2: nitrobenzene / 6 - 20 °C

2.1: 89 percent / tetrahydrofuran / 20 °C

3.1: KOt-Bu / tetrahydrofuran / Heating

3.2: 20 percent / TFA / toluene / 2 h / 0 °C

With aluminium trichloride; potassium tert-butylate; In tetrahydrofuran; nitrobenzene;
DOI:10.1021/jm021120f