Santalin B

Base Information

Chemical Name:Santalin B
CAS No.:51033-46-6
Molecular Formula:C34H28 O10
Molecular Weight:596.59
Hs Code.:
European Community (EC) Number:256-926-2
DSSTox Substance ID:DTXSID50965312
Nikkaji Number:J11.202J
Wikidata:Q82947499
Mol file:51033-46-6.mol

Synonyms:9H-Benzo(a)xanthen-9-one, 2,10-dihydroxy-5-(4-hydroxy-2-methoxyphenyl)-6-((4-hydroxy-3-methoxyphenyl)methyl)-1,3-dimethoxy-;Santalin B

Suppliers and Price of Santalin B

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Santalin B

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1022.5°Cat760mmHg
Flash Point:334.1°C
PSA：148.05000
Density:1.52g/cm³
LogP:6.21400
XLogP3:4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:7
Exact Mass:596.16824709
Heavy Atom Count:44
Complexity:1310

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C(=C3C(=CC4=CC(=C(C=C4O3)O)O)C2=C(C1=O)OC)CC5=CC(=C(C=C5)O)OC)C6=C(C=C(C=C6)O)OC

Technology Process of Santalin B

There total 9 articles about Santalin B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: (E)-4-(3-(4-hydroxy-2-methoxyphenyl)allyl)-2-methoxyphenol

: 6-hydroxy-3-(3-hydroxy-2,4-dimethoxyphenyl)-7H-chromen-7-one

: 51033-46-6
santalin B

Guidance literature:: With air; In methanol; acetonitrile; for 12h;
DOI:10.1002/anie.201302317

Reference yield:

: (E)-4-(3-(4-((tert-butyldimethylsilyl)oxy)-2-methoxyphenyl)allyl)-2-methoxyphenol

: 51033-46-6
santalin B

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2: air / methanol; acetonitrile / 12 h

With tetrabutyl ammonium fluoride; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1002/anie.201302317

Reference yield:

: 18111-34-7
3-bromo-2,6-dimethoxyphenol

: 51033-46-6
santalin B

Guidance literature:: Multi-step reaction with 6 steps

1: 1H-imidazole; dmap / N,N-dimethyl-formamide / 0.75 h / 0 - 20 °C / Inert atmosphere

2: palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / toluene; tetrahydrofuran / 2 h / 65 °C / Inert atmosphere

3: diisobutylaluminium hydride / dichloromethane / 1 h / -78 °C / Inert atmosphere

4: perchloric acid / acetic acid; water / 9 h / 20 °C / Inert atmosphere

5: 2,6-di-tert-butyl-pyridine / acetonitrile / 1.17 h / Inert atmosphere

6: air / methanol; acetonitrile / 12 h

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; 1H-imidazole; dmap; perchloric acid; 2,6-di-tert-butyl-pyridine; palladium diacetate; diisobutylaluminium hydride; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1002/anie.201302317