2-Cyclopentene-1-acetic acid, 5-[(phenylmethoxy)methyl]-, (1S,5R)-

Base Information

Chemical Name:2-Cyclopentene-1-acetic acid, 5-[(phenylmethoxy)methyl]-, (1S,5R)-
CAS No.:193071-32-8
Molecular Formula:C15H18O3
Molecular Weight:246.306
Hs Code.:
DSSTox Substance ID:DTXSID30453101
Wikidata:Q82274104
Mol file:193071-32-8.mol

Synonyms:2-Cyclopentene-1-acetic acid, 5-[(phenylmethoxy)methyl]-, (1S,5R)-;193071-32-8;DTXSID30453101

Suppliers and Price of 2-Cyclopentene-1-acetic acid, 5-[(phenylmethoxy)methyl]-, (1S,5R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Cyclopentene-1-acetic acid, 5-[(phenylmethoxy)methyl]-, (1S,5R)-

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:246.125594432
Heavy Atom Count:18
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C=CC(C1COCC2=CC=CC=C2)CC(=O)O
Isomeric SMILES:C1C=C[C@@H]([C@@H]1COCC2=CC=CC=C2)CC(=O)O

Technology Process of 2-Cyclopentene-1-acetic acid, 5-[(phenylmethoxy)methyl]-, (1S,5R)-

There total 10 articles about 2-Cyclopentene-1-acetic acid, 5-[(phenylmethoxy)methyl]-, (1S,5R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: C₂₁H₃₂O₂Si

: 193071-32-8
(1S)-cis-(5-Benzyloxymethylcyclopent-2-en-1-yl)acetic acid

Guidance literature:: In xylene; at 180 ℃; for 18h;
DOI:10.1055/s-2007-967937

Reference yield: 83.0%

: 261511-24-4
[(1S)-cis-1-(4-Benzyloxymethylcyclopent-2-en-1-yloxy)ethenyloxy] tert-butyldimethylsilane

: 193071-32-8
(1S)-cis-(5-Benzyloxymethylcyclopent-2-en-1-yl)acetic acid

Guidance literature:: [(1S)-cis-1-(4-Benzyloxymethylcyclopent-2-en-1-yloxy)ethenyloxy] tert-butyldimethylsilane; In xylene; at 190 ℃; for 18h;

With sodium hydroxide; water; In tetrahydrofuran; for 2h;
DOI:10.1039/a907522d

Reference yield:

: 193071-31-7
(1S)-cis-4-Benzyloxymethylcyclopent-2-en-1-yl acetate

: 193071-32-8
(1S)-cis-(5-Benzyloxymethylcyclopent-2-en-1-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi; DIPA; HMPA / tetrahydrofuran; hexane / 0.33 h / -78 °C

1.2: tetrahydrofuran / -78 - 20 °C

2.1: 87 percent / xylene / 18 h / 180 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; xylene; 2.1: Claisen-Ireland rearrangement reaction;
DOI:10.1055/s-2007-967937