N-(4-hydroxyphenethyl)maleimide

Base Information

Chemical Name:N-(4-hydroxyphenethyl)maleimide
CAS No.:19311-72-9
Molecular Formula:C12H11NO3
Molecular Weight:217.224
Hs Code.:
DSSTox Substance ID:DTXSID80478965
Nikkaji Number:J1.844.005I
Mol file:19311-72-9.mol

Synonyms:19311-72-9;1H-Pyrrole-2,5-dione, 1-[2-(4-hydroxyphenyl)ethyl]-;N-(4-hydroxyphenethyl)maleimide;SCHEMBL7542262;DTXSID80478965;AKOS010245721;1-[2-(4-Hydroxyphenyl)ethyl]-1H-pyrrole-2,5-dione

Suppliers and Price of N-(4-hydroxyphenethyl)maleimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(4-hydroxyphenethyl)maleimide

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:298

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CCN2C(=O)C=CC2=O)O

Technology Process of N-(4-hydroxyphenethyl)maleimide

There total 6 articles about N-(4-hydroxyphenethyl)maleimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 108-31-6
maleic anhydride

: 51-67-2
tyrosamine

: 19311-72-9
((4-hydroxyphenyl)ethyl)maleimide

Guidance literature:: With acetic acid; at 90 ℃;
DOI:10.1002/chem.201901858

Reference yield: 51.0%

: N-[4-(thexyldimethylsilyloxy)phenethyl]maleimide

: 19311-72-9
((4-hydroxyphenyl)ethyl)maleimide

Guidance literature:: With tetrabutyl ammonium fluoride; In dichloromethane; at 20 ℃; for 1h;
DOI:10.3390/molecules23112902

Reference yield:

: 2-[4-(thexyldimethylsilyloxy)phenyl]ethanol

: 19311-72-9
((4-hydroxyphenyl)ethyl)maleimide

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C

2: tetrabutyl ammonium fluoride / dichloromethane / 1 h / 20 °C

With di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; triphenylphosphine; In tetrahydrofuran; dichloromethane; 1: |Mitsunobu Displacement;
DOI:10.3390/molecules23112902