viridifloric acid

Base Information

• Chemical Name: viridifloric acid
• CAS No.: 17233-93-1
• Molecular Formula: C₇H₁₄O₄
• Molecular Weight: 162.186
• Hs Code.: 2918290000
• Mol file: 17233-93-1.mol

Synonyms:Butanoicacid, 2,3-dihydroxy-2-(1-methylethyl)-, [R-(R*,R*)]-; Butyric acid,2,3-dihydroxy-2-isopropyl-, (2R,3R)- (8CI); (+)-(2'R,3'R)-Viridifloric acid;(+)-Viridifloric acid; (2R,3R)-Viridifloric acid; Viridifloric acid, (+)-;Viridiflorinoic acid, (+)-

Chemical Property of viridifloric acid

Chemical Property:

• Vapor Pressure: 1.11E-05mmHg at 25°C
• Melting Point: 119-121 °C(Solv: chloroform (67-66-3))
• Boiling Point: 331.7°Cat760mmHg
• PKA: 3.68±0.25(Predicted)
• Flash Point: 168.6°C
• PSA: 77.76000
• Density: 1.205g/cm³
• LogP: -0.16110

Purity/Quality:

97% ^*data from raw suppliers

(2R,3R)-ViridifloricAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (2R,3R)-Viridifloric Acid is an intermediate in the synthesis of (+)-Lycopsamine (L487525), which occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. They are being known as hepatotoxins and tumorigens.It has been shown that pyrrolizidine Alkaloid-Derived DNA Adducts, are the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation.

Technology Process of viridifloric acid

There total 27 articles about viridifloric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(1'R,2S,5R)-2-(t-butyl)-5-(1'hydroxyethyl)-5-isopropyl-1,3-dioxolan-4-one (132585-76-3) → (+)-viridifloric acid (17233-93-1)

Guidance literature:

With hydrogenchloride; for 3h; Heating;

DOI:10.1246/bcsj.63.3707

Reference yield: 71.0%

4(R)-(1-methylethyl)-2,2,5(R)-trimethyl-1,3-dioxolane-4-carboxylic acid (81816-10-6) → (+)-viridifloric acid (17233-93-1)

Guidance literature:

With water; trifluoroacetic acid; In chloroform; for 120h; Ambient temperature;

Reference yield:

(E)-2-(1-methylethyl)-2-butenoic acid (94773-28-1) → (+)-viridifloric acid (17233-93-1)

Guidance literature:

With dihydrogen peroxide; potassium nitrate; In acetonitrile;

DOI:10.1016/S0040-4020(01)82781-2

upstream raw materials:

(+/-)-trachelanthic acid

(E)-2-(1-methylethyl)-2-butenoic acid

(+/-)-trachelanthic acid

iso-lycopsamine

Downstream raw materials:

morifoline

4-methyl-2,3-pentanedione