Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-7-methyl-3-phenyl-1-(2-propenyl)-, ethyl ester

Base Information

Chemical Name:Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-7-methyl-3-phenyl-1-(2-propenyl)-, ethyl ester
CAS No.:131448-08-3
Molecular Formula:C₂₀H₁₉N₃O₄
Molecular Weight:365.389
Hs Code.:
DSSTox Substance ID:DTXSID30157051
Wikidata:Q83025171

Synonyms:BRN 3570743;131448-08-3;Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-7-methyl-3-phenyl-1-(2-propenyl)-, ethyl ester;DTXSID30157051;LS-134108

Suppliers and Price of Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-7-methyl-3-phenyl-1-(2-propenyl)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-7-methyl-3-phenyl-1-(2-propenyl)-, ethyl ester

Chemical Property:

Vapor Pressure:4.2E-12mmHg at 25°C
Boiling Point:549°Cat760mmHg
Flash Point:285.8°C
Density:1.265g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:365.13755610
Heavy Atom Count:27
Complexity:602

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C2C(=NC(=C1)C)N(C(=O)N(C2=O)C3=CC=CC=C3)CC=C

Technology Process of Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-7-methyl-3-phenyl-1-(2-propenyl)-, ethyl ester

There total 3 articles about Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-7-methyl-3-phenyl-1-(2-propenyl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 131448-03-8
ethyl 7-methyl-3-phenyl-2,4-dioxo-1,2,3,4-tetrahydropyrido<2,3-d>pyrimidine-5-carboxylate

: 131448-08-3
1-Allyl-7-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid ethyl ester

Guidance literature:: With sodium ethanolate; In ethanol; for 14h; Heating;

Reference yield:

: 103-71-9
phenyl isocyanate

: 131448-08-3
1-Allyl-7-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) NaOC₂H₅ / 1.) 45 min, 60 deg C 2.) benzene, EtOH, 2 h, reflux

2: 68 percent / NaOC₂H₅ / ethanol / 14 h / Heating

With sodium ethanolate; In ethanol;

Reference yield:

: 91558-58-6
diethyl 2-amino-6-methylpyridine-3,4-dicarboxylate

: 131448-08-3
1-Allyl-7-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) NaOC₂H₅ / 1.) 45 min, 60 deg C 2.) benzene, EtOH, 2 h, reflux

2: 68 percent / NaOC₂H₅ / ethanol / 14 h / Heating

With sodium ethanolate; In ethanol;