Kemptide

Base Information

• Chemical Name: Kemptide
• CAS No.: 65189-71-1
• Molecular Formula: C32H61 N13 O9
• Molecular Weight: 771.91
• Hs Code.: 35079090
• NSC Number: 332190
• DSSTox Substance ID: DTXSID80983766
• Mol file: 65189-71-1.mol

Synonyms:kemptide;Leu-Arg-Arg-Ala-Ser-Leu-Gly;leucyl-arginyl-arginyl-alanyl-seryl-leucyl-glycine

Chemical Property of Kemptide

Chemical Property:

• PKA: 3.32±0.10(Predicted)
• PSA: 381.95000
• Density: 1.433g/cm3
• LogP: 0.99700
• Storage Temp.: −20°C
• Solubility.: H2O: 20 mg/mL
• Water Solubility.: Soluble in water (20 mg/ml).
• XLogP3: -5.7
• Hydrogen Bond Donor Count: 13
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 26
• Exact Mass: 771.47152057
• Heavy Atom Count: 54
• Complexity: 1320

Purity/Quality:

99% ^*data from raw suppliers

Kemptide ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NCC(=O)O)N
• Uses: Kemptide, phosphate acceptor, is shown to be a basic serine-containing heptapeptide corresponding to a sequence from pig liver pyruvate kinase. This synthetic peptide is a substrate of PKA (cyclic AMP-dependent protein kinase) and is phosphorylated and activated after microinjection into Xenopus oocytes. Exposure of Kemptide to insulin has demonstrated an increase in activation of this agent, which can be inhibited by the catalytic subunit of phosphatase 2A.