Propanedinitrile, [4'-(5-methyl-1,3-benzodithiol-2-yl)[1,1'-biphenyl]-4-yl]-

Base Information

• Chemical Name: Propanedinitrile, [4'-(5-methyl-1,3-benzodithiol-2-yl)[1,1'-biphenyl]-4-yl]-
• CAS No.: 193980-17-5
• Molecular Formula: C23H16N2S2
• Molecular Weight: 384.525
• Mol file: 193980-17-5.mol

Synonyms:

Chemical Property of Propanedinitrile, [4'-(5-methyl-1,3-benzodithiol-2-yl)[1,1'-biphenyl]-4-yl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanedinitrile, [4'-(5-methyl-1,3-benzodithiol-2-yl)[1,1'-biphenyl]-4-yl]-

There total 4 articles about Propanedinitrile, [4'-(5-methyl-1,3-benzodithiol-2-yl)[1,1'-biphenyl]-4-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4-bromophenyl)bromobenzene (92-86-4) → 2-[4'-(5-Methyl-benzo[1,3]dithiol-2-yl)-biphenyl-4-yl]-malononitrile (193980-17-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 69 percent / n-BuLi / diethyl ether / 1.) -15 deg C, 0.5 h, 2.) -78 deg C to r.t., 1 h

2: TsOH / benzene / 1 h / Heating

3: 60 percent / Pd(PPh₃)4 / tetrahydrofuran / 4 h / Heating

4: TsOH / benzene / 1 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; diethyl ether; benzene;

DOI:10.1039/a701626c

Reference yield:

4-formyl-4'-bromobiphenyl (50670-58-1) → 2-[4'-(5-Methyl-benzo[1,3]dithiol-2-yl)-biphenyl-4-yl]-malononitrile (193980-17-5)

Guidance literature:

Multi-step reaction with 3 steps

1: TsOH / benzene / 1 h / Heating

2: 60 percent / Pd(PPh₃)4 / tetrahydrofuran / 4 h / Heating

3: TsOH / benzene / 1 h / Heating

With toluene-4-sulfonic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; benzene;

DOI:10.1039/a701626c

Reference yield:

2-(4’-bromo-[1,1’-biphenyl]-4-yl)-1,3-dioxolane (214745-69-4) → 2-[4'-(5-Methyl-benzo[1,3]dithiol-2-yl)-biphenyl-4-yl]-malononitrile (193980-17-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / Pd(PPh₃)4 / tetrahydrofuran / 4 h / Heating

2: TsOH / benzene / 1 h / Heating

With toluene-4-sulfonic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; benzene;

DOI:10.1039/a701626c

upstream raw materials:

3,4-dimercaptotoluene

2-(4'-Formyl-biphenyl-4-yl)-malononitrile

4-(4-bromophenyl)bromobenzene

4-formyl-4'-bromobiphenyl