4-[(2-Phenylcyclopropyl)sulfonyl]morpholine

Base Information

Chemical Name:4-[(2-Phenylcyclopropyl)sulfonyl]morpholine
CAS No.:17299-25-1
Molecular Formula:C13H17 N O3 S
Molecular Weight:267.344
Hs Code.:
NSC Number:140234
DSSTox Substance ID:DTXSID00300971
ChEMBL ID:CHEMBL310956

Synonyms:17299-25-1;4-[(2-Phenylcyclopropyl)sulfonyl]morpholine;Morpholine, trans-;NSC140234;CHEMBL310956;DTXSID00300971;NSC-140234

Suppliers and Price of 4-[(2-Phenylcyclopropyl)sulfonyl]morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-[(2-Phenylcyclopropyl)sulfonyl]morpholine

Chemical Property:

Vapor Pressure:1.32E-07mmHg at 25°C
Boiling Point:430.2°Cat760mmHg
Flash Point:214°C
Density:1.32g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:267.09291458
Heavy Atom Count:18
Complexity:378

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1S(=O)(=O)C2CC2C3=CC=CC=C3

Technology Process of 4-[(2-Phenylcyclopropyl)sulfonyl]morpholine

There total 4 articles about 4-[(2-Phenylcyclopropyl)sulfonyl]morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 17299-32-0
(E)-4-<(2-phenylethynyl)sulfonyl>morpholine

: dimethoxysulphonium methylide

: 110417-64-6
N-<(2-phenyl-2-propen-1-yl)sulfonyl>morpholine

: 17299-25-1
trans-N-<(2-phenylcyclopropyl)sulfonyl>morpholine

Guidance literature:: In dimethyl sulfoxide; at 60 ℃; for 4h;
DOI:10.1021/jm00395a010

Reference yield:

: 22457-12-1
4-((bromomethyl)sulfonyl)morpholine

: 17299-25-1
trans-N-<(2-phenylcyclopropyl)sulfonyl>morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 50percent aq. NaOH, Bu₄N⁽¹⁺⁾*HSO₄^(1-), HMPT

2: 50 percent / dimethylsulfoxide / 4 h / 60 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dimethyl sulfoxide;
DOI:10.1021/jm00395a010