3(2H)-Pyridazinone, 4,5-dihydro-5-(4-aminophenyl)-6-methyl-

Base Information

Chemical Name:3(2H)-Pyridazinone, 4,5-dihydro-5-(4-aminophenyl)-6-methyl-
CAS No.:117903-07-8
Molecular Formula:C₁₁H₁₃N₃O
Molecular Weight:203.244
Hs Code.:
DSSTox Substance ID:DTXSID20922573
Mol file:117903-07-8.mol

Synonyms:3(2H)-Pyridazinone, 4,5-dihydro-5-(4-aminophenyl)-6-methyl-;117903-07-8;4,5-Dihydro-5-(4-aminophenyl)-6-methyl-3(2H)-pyridazinone;5-(p-Aminophenyl)-6-methyl-4,5-dihydro-3(2H)-pyridazinone;3(2H)-Pyridazinone, 5-(4-aminophenyl)-4,5-dihydro-6-methyl-;DTXSID20922573;LS-129867;5-(4-Aminophenyl)-6-methyl-4,5-dihydropyridazin-3-ol

Suppliers and Price of 3(2H)-Pyridazinone, 4,5-dihydro-5-(4-aminophenyl)-6-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3(2H)-Pyridazinone, 4,5-dihydro-5-(4-aminophenyl)-6-methyl-

Chemical Property:

Refractive Index:1.652
Density:1.3g/cm³
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:203.105862047
Heavy Atom Count:15
Complexity:280

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NNC(=O)CC1C2=CC=C(C=C2)N

Technology Process of 3(2H)-Pyridazinone, 4,5-dihydro-5-(4-aminophenyl)-6-methyl-

There total 4 articles about 3(2H)-Pyridazinone, 4,5-dihydro-5-(4-aminophenyl)-6-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.3%

: 117903-14-7
3-p.aminophenyl-4-oxopentanoic acid

: 117903-07-8
5-p.aminophenyl-6-methyl-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: With hydrazine hydrate; In ethanol; acetic acid; for 5h; Heating;

Reference yield:

: 93159-92-3
(2-oxo-1-phenyl-propyl)-malonic acid diethyl ester

: 117903-07-8
5-p.aminophenyl-6-methyl-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 4 steps

1: 66 percent / fuming nitric acid / 1.5 h / below 5 deg C

2: 75 percent / 48percent HBr / acetic acid / 6 h / Heating

3: 96 percent / hydrogen / 5percent Pd/C / ethanol / 2280 Torr / Ambient temperature

4: 65.3 percent / hydrazine hydrate / acetic acid; ethanol / 5 h / Heating

With hydrogen bromide; hydrogen; nitric acid; hydrazine hydrate; palladium on activated charcoal; In ethanol; acetic acid;

Reference yield:

: 117903-12-5
ethyl-2-ethoxycarbonyl-3-p.nitrophenyl-4-oxopentanoate

: 117903-07-8
5-p.aminophenyl-6-methyl-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / 48percent HBr / acetic acid / 6 h / Heating

2: 96 percent / hydrogen / 5percent Pd/C / ethanol / 2280 Torr / Ambient temperature

3: 65.3 percent / hydrazine hydrate / acetic acid; ethanol / 5 h / Heating

With hydrogen bromide; hydrogen; hydrazine hydrate; palladium on activated charcoal; In ethanol; acetic acid;