3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-, 3-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl] 5-ethyl ester, (4S)-

Base Information

Chemical Name:3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-, 3-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl] 5-ethyl ester, (4S)-
CAS No.:194347-08-5
Molecular Formula:C30H31NO6
Molecular Weight:501.579
Hs Code.:

3,5-Pyridinedicarboxylic acid,
1,4-dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-,
3-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl] 5-ethyl ester, (4S)-

Synonyms:

Suppliers and Price of 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-, 3-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl] 5-ethyl ester, (4S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-, 3-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl] 5-ethyl ester, (4S)-

Chemical Property:

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-, 3-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl] 5-ethyl ester, (4S)-

There total 2 articles about 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-methyl-6-phenyl-4-(phenylethynyl)-, 3-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl] 5-ethyl ester, (4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 2579-22-8
Phenylpropargyl aldehyde

: 124413-63-4
ethyl 3-amino-3-phenyl-2-propenoate

: 244765-74-0
(R)-(+)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl acetoacetate

: 194347-09-6
(R)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-((R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl) ester 5-ethyl ester

: 194347-08-5
(S)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-((R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl) ester 5-ethyl ester

Guidance literature:: In ethanol; at 80 ℃;
DOI:10.1021/jm980688e

Reference yield:

: 22323-82-6,36543-79-0
(S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol

: 194347-08-5
(S)-2-Methyl-6-phenyl-4-phenylethynyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-((R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl) ester 5-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / NaOAc / toluene / 4 h

2: 47 percent / ethanol / 80 °C

With sodium acetate; In ethanol; toluene;
DOI:10.1021/jm980688e