BENZYL-(1-METHYL-PIPERIDIN-4-YL)-AMINE

Base Information

• Chemical Name: BENZYL-(1-METHYL-PIPERIDIN-4-YL)-AMINE
• CAS No.: 194538-07-3
• Molecular Formula: C13H20N2
• Molecular Weight: 204.315
• Mol file: 194538-07-3.mol

Synonyms:1-methyl-4-(benzylamino)piperidine;Benzyl-(1-methyl-piperidin-4-yl)-amine;Benzyl-(1-methyl-[4]piperidyl)-amin;

Chemical Property of BENZYL-(1-METHYL-PIPERIDIN-4-YL)-AMINE

Chemical Property:

• Boiling Point: 168-172 °C(Press: 17 Torr)
• PKA: 9.41±0.20(Predicted)
• PSA: 15.27000
• Density: 1.01±0.1 g/cm3(Predicted)
• LogP: 2.19920

Purity/Quality:

98%min ^*data from raw suppliers

N-benzyl-1-methylpiperidin-4-amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of BENZYL-(1-METHYL-PIPERIDIN-4-YL)-AMINE

There total 2 articles about BENZYL-(1-METHYL-PIPERIDIN-4-YL)-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Methyl-4-piperidone (1445-73-4) + benzylamine (100-46-9) → benzyl-(1-methyl-[4]piperidyl)-amine (194538-07-3)

Guidance literature:

With ethanol; platinum; Hydrogenation;

DOI:10.1021/ja01192a011

Reference yield:

→ benzyl-(1-methyl-[4]piperidyl)-amine (194538-07-3)

Guidance literature:

DOI:10.1021/jm00336a010

Reference yield: 97.0%

benzyl-(1-methyl-[4]piperidyl)-amine (194538-07-3) + 4-Phenylbutyric acid (1821-12-1) → N-Benzyl-N-(1-methyl-piperidin-4-yl)-4-phenyl-butyramide

Guidance literature:

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In N,N-dimethyl-formamide; at 100 ℃; for 3h; under 30 Torr;

DOI:10.1016/S0040-4039(97)01136-2

upstream raw materials:

1-Methyl-4-piperidone

benzylamine