2,3-dimethylquinoxaline-5-carboxylic Acid

Base Information

Chemical Name:2,3-dimethylquinoxaline-5-carboxylic Acid
CAS No.:6924-67-0
Molecular Formula:C11H10 N2 O2
Molecular Weight:202.213
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40378018
Wikidata:Q82167451
Mol file:6924-67-0.mol

Synonyms:2,3-dimethylquinoxaline-5-carboxylic Acid;6924-67-0;2,3-DIMETHYL-QUINOXALINE-5-CARBOXYLIC ACID;MFCD06245382;SCHEMBL3557070;DTXSID40378018;BBL100567;STL554361;AKOS005254656;MS-20040;FT-0694780;EN300-9428469;2,3-DIMETHYL-QUINOXALINE-5-CARBOXYLICACID

Suppliers and Price of 2,3-dimethylquinoxaline-5-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-dimethylquinoxaline-5-carboxylicAcid
10mg
$ 45.00

SynQuest Laboratories
2,3-Dimethylquinoxaline-5-carboxylic acid
500 mg
$ 429.00

American Custom Chemicals Corporation
2,3-DIMETHYL-QUINOXALINE-5-CARBOXYLIC ACID 95.00%
500MG
$ 967.52

Total 8 raw suppliers

Chemical Property of 2,3-dimethylquinoxaline-5-carboxylic Acid

Chemical Property:

Vapor Pressure:8.13E-07mmHg at 25°C
Boiling Point:391.1°C at 760 mmHg
Flash Point:190.3°C
PSA：63.08000
Density:1.303g/cm³
LogP:1.94480
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:202.074227566
Heavy Atom Count:15
Complexity:257

Purity/Quality:

NLT 98% ^*data from raw suppliers

2,3-dimethylquinoxaline-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=CC=CC(=C2N=C1C)C(=O)O
Uses 2,3-dimethylquinoxaline-5-carboxylic acid (cas# 6924-67-0) is a useful as a reactant or reagent in preparation of heteroaryl heptanamide derivates for use in treatment of parasitic diseases.

Technology Process of 2,3-dimethylquinoxaline-5-carboxylic Acid

There total 2 articles about 2,3-dimethylquinoxaline-5-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 431-03-8
dimethylglyoxal

: 603-81-6
2,3-diaminobenzoic acid

: 6924-67-0
2,3-dimethyl-5-quinoxalinecarboxylic acid

Guidance literature:: In acetic acid; for 2h; Heating;
DOI:10.1135/cccc19840285

Reference yield:

: 6924-67-0
2,3-dimethyl-5-quinoxalinecarboxylic acid

Guidance literature:: 3-Nitro-2-amino-benzoesaeure, 1. Hydrieren in EtOH, 2. Diacetyl, wss.K2CO3-Lsg;
DOI:10.1021/jo01022a531

Reference yield: 43.0%

: (1S,3r)-3-(5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl)cyclobutan-1-amine dihydrochloride

: 6924-67-0
2,3-dimethyl-5-quinoxalinecarboxylic acid

: N-(trans-3-(5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl)cyclobutyl)-2,3-dimethylquinoxaline-5-carboxamide

Guidance literature:: 2,3-dimethyl-5-quinoxalinecarboxylic acid; With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; acetonitrile; Inert atmosphere;

(1S,3r)-3-(5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl)cyclobutan-1-amine dihydrochloride; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/acs.jmedchem.1c01264