1-(p-Chlorophenyl)-2-methylpiperazine

Base Information

Chemical Name:1-(p-Chlorophenyl)-2-methylpiperazine
CAS No.:55117-80-1
Molecular Formula:C11H15 Cl N2
Molecular Weight:210.706
Hs Code.:2933599090
European Community (EC) Number:259-488-0
NSC Number:97022
DSSTox Substance ID:DTXSID701286802
Nikkaji Number:J153.488B
ChEMBL ID:CHEMBL1879559
Mol file:55117-80-1.mol

Synonyms:1-(4-chlorophenyl)-2-methylpiperazine;1-(p-Chlorophenyl)-2-methylpiperazine;55117-80-1;EINECS 259-488-0;Piperazine, 1-(p-chlorophenyl)-2-methyl-;Piperazine, 1-(4-chlorophenyl)-2-methyl-;NSC 97022;BRN 4421355;MLS002703360;NSC97022;1-(4-Chloro-phenyl)-2-methyl-piperazine;SCHEMBL335933;CHEMBL1879559;DTXSID701286802;WLN: T6M DNTJ C1 DR DG;NSC-97022;AKOS014269301;SMR001570082;LS-111304;FT-0605686

Suppliers and Price of 1-(p-Chlorophenyl)-2-methylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-CHLOROPHENYL)-2-METHYLPIPERAZINE 95.00%
5MG
$ 505.67

Total 8 raw suppliers

Chemical Property of 1-(p-Chlorophenyl)-2-methylpiperazine

Chemical Property:

Vapor Pressure:8.75E-05mmHg at 25°C
Boiling Point:340.2°C at 760 mmHg
Flash Point:159.5°C
PSA：15.27000
Density:1.11g/cm³
LogP:2.53190
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:210.0923762
Heavy Atom Count:14
Complexity:178

Purity/Quality:

99% ^*data from raw suppliers

1-(4-CHLOROPHENYL)-2-METHYLPIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CNCCN1C2=CC=C(C=C2)Cl

Technology Process of 1-(p-Chlorophenyl)-2-methylpiperazine

There total 3 articles about 1-(p-Chlorophenyl)-2-methylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 849106-48-5
4-(4-chloro-phenyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester

: 55117-80-1
1-(4-chloro-phenyl)-2-methyl-piperazine

Guidance literature:: In 1,4-dioxane; hydrogenchloride;

Reference yield:

: 106-39-8
bromochlorobenzene

: 55117-80-1
1-(4-chloro-phenyl)-2-methyl-piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium t-butanolate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 10 h / 120 °C

2: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

With hydrogenchloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In 1,4-dioxane;

Reference yield:

: 120737-59-9
3-methyl-piperazine-1-carboxylic acid tert-butyl ester

: 55117-80-1
1-(4-chloro-phenyl)-2-methyl-piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium t-butanolate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 10 h / 120 °C

2: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

With hydrogenchloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In 1,4-dioxane;