3H-Benzo(C)quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl-

Base Information

Chemical Name:3H-Benzo(C)quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl-
CAS No.:194979-95-8
Molecular Formula:C15H17NO
Molecular Weight:227.30200
Hs Code.:
UNII:LIV8A6AE5F
Nikkaji Number:J1.431.301J
Wikidata:Q27283010
Pharos Ligand ID:L1TCZCW5XYQT
ChEMBL ID:CHEMBL118319
Mol file:194979-95-8.mol

Synonyms:AS-601811;194979-95-8;3H-Benzo(C)quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl-;UNII-LIV8A6AE5F;LIV8A6AE5F;CHEMBL118319;4,8-Dimethyl-1,2,5,6-tetrahydro-3H-pyrido[1,2-a]quinolin-3-one;starbld0006591;D0P9EL;SCHEMBL6819198;BDBM50092492;AKOS040750585;Q27283010;4,8-dimethyl-1,2,5,6-tetrahydrobenzo[f]quinolizin-3-one;4,8-dimethyl-1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one;4,8-Dimethyl-2,3,5,6-tetrahydro-1H-benzo[c]quinolizin-3-one;1,2,5,6-Tetrahydro-4,8-dimethyl-3H-benzo[c]quinolizine-3-one;4,8-dimethyl-1,2,5,6 tetrahydro-(11H)-benzo[c]quinolizine-3-one;4,8-Dimethyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-3-one;8-methyl-2,3,5,6-tetrahydro-4-methyl-(1h)-benzo[c]quinolizin-3-one

Suppliers and Price of 3H-Benzo(C)quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3H-Benzo(C)quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl-

Chemical Property:

PSA：20.31000
LogP:3.05940
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:227.131014166
Heavy Atom Count:17
Complexity:371

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)N3CCC(=O)C(=C3CC2)C

Technology Process of 3H-Benzo(C)quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl-

There total 5 articles about 3H-Benzo(C)quinolizin-3-one, 1,2,5,6-tetrahydro-4,8-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 4,8-dimethyl-1,2,3,4,5,6-hexahydrobenzo[c]quinolizin-3(4aH)-one

: 194979-95-8
4,8-dimethyl-2,3,5,6-tetrahydro-(1H)-benzo[c]quinolizin-3-one

Guidance literature:: With mercury(II) diacetate; ethylene diamine tetraacetic acid tetrasodium salt; acetic acid; at 90 ℃; for 2h;
DOI:10.1021/jm000945r

Reference yield:

: 6-methyl-2-methylsulfanyl-1-(3-oxo-pentyl)-3,4-dihydro-quinolinium

: 194979-95-8
4,8-dimethyl-2,3,5,6-tetrahydro-(1H)-benzo[c]quinolizin-3-one

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; for 0.333333h; Heating;
DOI:10.1021/jo000603t

Reference yield:

: 20150-83-8
6-methyl-1,2,3,4-tetrahydroquinolin-2-one

: 194979-95-8
4,8-dimethyl-2,3,5,6-tetrahydro-(1H)-benzo[c]quinolizin-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / Lawesson's reagent / toluene / 0.25 h / Heating

2: 68 percent / K₂CO₃; 18-crown-6 / tetrahydrofuran / 0 - 25 °C

3: toluene / 0.25 h / Heating

4: 152 mg / 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 0.33 h / Heating

With Lawessons reagent; 18-crown-6 ether; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; toluene; 1: Substitution / 2: Alkylation / 3: Methylation / 4: Cyclization;
DOI:10.1021/jo000603t