1H-Phosphole, 1-(4-chlorophenyl)-2,3-dihydro-4-methyl-, 1-oxide

Base Information

Chemical Name:1H-Phosphole, 1-(4-chlorophenyl)-2,3-dihydro-4-methyl-, 1-oxide
CAS No.:195317-29-4
Molecular Formula:C11H12ClOP
Molecular Weight:226.642
Hs Code.:
DSSTox Substance ID:DTXSID60455850
Nikkaji Number:J1.711.459J
Mol file:195317-29-4.mol

Synonyms:1H-Phosphole, 1-(4-chlorophenyl)-2,3-dihydro-4-methyl-, 1-oxide;195317-29-4;DTXSID60455850;1-(4-Chlorophenyl)-3-methyl-4,5-dihydro-1H-phosphole 1-oxide

Suppliers and Price of 1H-Phosphole, 1-(4-chlorophenyl)-2,3-dihydro-4-methyl-, 1-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1H-Phosphole, 1-(4-chlorophenyl)-2,3-dihydro-4-methyl-, 1-oxide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:226.0314297
Heavy Atom Count:14
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CP(=O)(CC1)C2=CC=C(C=C2)Cl

Technology Process of 1H-Phosphole, 1-(4-chlorophenyl)-2,3-dihydro-4-methyl-, 1-oxide

There total 4 articles about 1H-Phosphole, 1-(4-chlorophenyl)-2,3-dihydro-4-methyl-, 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 106-39-8
bromochlorobenzene

: 823-14-3
1-chloro-3-methyl-2-phospholene 1-oxide

: 195317-29-4
1-(4'-chlorophenyl)-3-methyl-2-phospholene 1-oxide

Guidance literature:: With magnesium; In tetrahydrofuran; at 20 ℃; for 6h;
DOI:10.1002/jhet.5570390109

Reference yield:

: 695-60-3
1-methoxy-3-methyl-2-phospholene 1-oxide

: 195317-29-4
1-(4'-chlorophenyl)-3-methyl-2-phospholene 1-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 24 h / 20 °C

2: 50 percent / magnesium / tetrahydrofuran / 6 h / 20 °C

With thionyl chloride; magnesium; In tetrahydrofuran;
DOI:10.1002/jhet.5570390109

Reference yield:

: 106-39-8
bromochlorobenzene

: 195317-29-4
1-(4'-chlorophenyl)-3-methyl-2-phospholene 1-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: Mg / tetrahydrofuran / 0.67 h / 0 °C

2: 0.60 g / tetrahydrofuran / 6 h / 20 °C

With magnesium; In tetrahydrofuran;
DOI:10.1080/10426500212255