Ethyl 2-(2,1,3-benzothiadiazol-5-yl)acetate

Base Information

Chemical Name:Ethyl 2-(2,1,3-benzothiadiazol-5-yl)acetate
CAS No.:195505-47-6
Molecular Formula:C10H10N2O2S
Molecular Weight:222.268
Hs Code.:
DSSTox Substance ID:DTXSID20456222
Wikidata:Q82278497
Mol file:195505-47-6.mol

Synonyms:195505-47-6;Ethyl 2-(benzo[c][1,2,5]thiadiazol-5-yl)acetate;ethyl 2-(2,1,3-benzothiadiazol-5-yl)acetate;2,1,3-Benzothiadiazole-5-acetic acid, ethyl ester;MFCD28127334;2,1,3-Benzothiadiazole-5-acetic acid ethyl ester;SCHEMBL981575;DTXSID20456222;AAZNXGHXCQJHGD-UHFFFAOYSA-N;AMY24658;VHA50547;AKOS037651283;CS-16383;SY251592;CS-0096460;FT-0727385;C73712;Ethyl2-(benzo[c][1,2,5]thiadiazol-5-yl)acetate

Suppliers and Price of Ethyl 2-(2,1,3-benzothiadiazol-5-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of Ethyl 2-(2,1,3-benzothiadiazol-5-yl)acetate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:222.04629874
Heavy Atom Count:15
Complexity:238

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=CC2=NSN=C2C=C1

Technology Process of Ethyl 2-(2,1,3-benzothiadiazol-5-yl)acetate

There total 4 articles about Ethyl 2-(2,1,3-benzothiadiazol-5-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 85907-78-4
ethyl 2-(3,4-diaminophenyl)acetate

: 195505-47-6
ethyl 2-(2,1,3-benzothiadiazol-5-yl)-acetate

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(97)10151-2

Reference yield:

: 1197-55-3
4-aminophenylacetic acid

: 195505-47-6
ethyl 2-(2,1,3-benzothiadiazol-5-yl)-acetate

Guidance literature:: Multi-step reaction with 4 steps

1: 2.) HNO₃, AcOH

2: HCl / Heating

3: 90 percent / H₂ / Pd/C / ethanol

4: 75 percent / SOCl₂, DMF

With hydrogenchloride; thionyl chloride; hydrogen; nitric acid; acetic acid; N,N-dimethyl-formamide; palladium on activated charcoal; In ethanol;
DOI:10.1016/S0960-894X(97)10151-2

Reference yield:

: 90916-02-2
4-Acetamino-3-nitro-phenylessigsaeure

: 195505-47-6
ethyl 2-(2,1,3-benzothiadiazol-5-yl)-acetate

Guidance literature:: Multi-step reaction with 3 steps

1: HCl / Heating

2: 90 percent / H₂ / Pd/C / ethanol

3: 75 percent / SOCl₂, DMF

With hydrogenchloride; thionyl chloride; hydrogen; N,N-dimethyl-formamide; palladium on activated charcoal; In ethanol;
DOI:10.1016/S0960-894X(97)10151-2