(1S,2S)-1,2-Diphenyl-2-(acetylamino)ethanol

Base Information

Chemical Name:(1S,2S)-1,2-Diphenyl-2-(acetylamino)ethanol
CAS No.:195625-00-4
Molecular Formula:C16H17NO2
Molecular Weight:255.316
Hs Code.:
DSSTox Substance ID:DTXSID20426283
Nikkaji Number:J1.912.161E
Wikidata:Q82239225

Synonyms:(1S,2S)-1,2-Diphenyl-2-(acetylamino)ethanol;195625-00-4;ZINC01510077;DTXSID20426283

Suppliers and Price of (1S,2S)-1,2-Diphenyl-2-(acetylamino)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (1S,2S)-1,2-Diphenyl-2-(acetylamino)ethanol

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:255.125928785
Heavy Atom Count:19
Complexity:281

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(C1=CC=CC=C1)C(C2=CC=CC=C2)O
Isomeric SMILES:CC(=O)N[C@@H](C1=CC=CC=C1)[C@H](C2=CC=CC=C2)O

Technology Process of (1S,2S)-1,2-Diphenyl-2-(acetylamino)ethanol

There total 9 articles about (1S,2S)-1,2-Diphenyl-2-(acetylamino)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 645-49-8
cis-stilben

: 79-15-2
N-bromoacetamide

: 195625-00-4
N-(L(g)-threo-α'-hydroxy-bibenzyl-α-yl)-acetamid; N-acetyl-(-)-isodiphenylhydroxyethylamine

: 195625-08-2
threo-2-Acetamino-1.2-diphenyl-aethan-1-ol

Guidance literature:: With potassium hydroxide; Hydroquinone 1,4-phthalazinediyl diether; Amberlite XAD-16-OsO₄; In isopropyl alcohol; at 4 ℃; for 24h; Title compound not separated from byproducts;
DOI:10.1039/b303022a

Reference yield:

: 103-30-0
(E)-1,2-diphenyl-ethene

: 79-15-2
N-bromoacetamide

: 195625-00-4
N-(L(g)-threo-α'-hydroxy-bibenzyl-α-yl)-acetamid; N-acetyl-(-)-isodiphenylhydroxyethylamine

: 195625-08-2
threo-2-Acetamino-1.2-diphenyl-aethan-1-ol

Guidance literature:: With lithium hydroxide; Hydroquinone 1,4-phthalazinediyl diether; K2; In tert-butyl alcohol; at 4 ℃; for 20h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1002/anie.199714831

Reference yield:

: 7431-13-2,23070-96-4,84388-60-3,133670-89-0
threo-2-acetamido-1,2-diphenylethan-1-ol

: 108-24-7
acetic anhydride

: threo-2-acetamido-1,2-diphenylethyl acetate

: 195625-00-4
N-(L(g)-threo-α'-hydroxy-bibenzyl-α-yl)-acetamid; N-acetyl-(-)-isodiphenylhydroxyethylamine

: 195625-08-2
threo-2-Acetamino-1.2-diphenyl-aethan-1-ol

: 101023-17-0,107525-64-4
threo-2-acetamido-1,2-diphenylethyl acetate

Guidance literature:: With Boc-(?-Me)-L-His-D-Pro-CSNH-Aib-L-Phe-OMe; triethylamine; In toluene; at 25 ℃; for 3h; Resolution of racemate;
DOI:10.1021/jo200403g