(5-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol

Base Information

• Chemical Name: (5-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol
• CAS No.: 197577-35-8
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.073
• Mol file: 197577-35-8.mol

Synonyms:

Chemical Property of (5-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol

Chemical Property:

• PSA: 29.46000
• LogP: 2.01270

Purity/Quality:

99%, ^*data from raw suppliers

(5-Bromo-2,3-dihydro-1-benzofuran-2-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol

There total 3 articles about (5-BroMo-2,3-dihydrobenzofuran-2-yl)Methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ 5-bromo-2-hydroxymethyl-2,3-dihydrobenzo[b]furan (197577-35-8)

Guidance literature:

Reference yield:

2-allyl-4-bromophenol (13997-74-5) → 5-bromo-2-hydroxymethyl-2,3-dihydrobenzo[b]furan (197577-35-8)

Guidance literature:

Multi-step reaction with 2 steps

1: m-CPBA / CH₂Cl₂ / Heating

2: methanesulfonic acid / CH₂Cl₂ / 20 °C

With methanesulfonic acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1016/j.tet.2005.12.026

Reference yield:

4-Bromo-2-oxiranylmethyl-phenol → 5-bromo-2-hydroxymethyl-2,3-dihydrobenzo[b]furan (197577-35-8)

Guidance literature:

With Kieselgel 60; In dichloromethane; for 24h; Ambient temperature;

DOI:10.1021/jm00371a003

upstream raw materials:

2-allyl-4-bromophenol

Downstream raw materials:

5-bromo-1-benzofuran-2-carbaldehyde

5-bromo-2,3-dihydro-1-benzofuran-2-carboxylic acid