2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide

Base Information

• Chemical Name: 2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide
• CAS No.: 1978-70-7
• Molecular Formula: C11H12F3NO
• Molecular Weight: 231.218
• DSSTox Substance ID: DTXSID401232113
• Mol file: 1978-70-7.mol

Synonyms:2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide;1978-70-7;Propanamide, 2-methyl-N-[4-(trifluoromethyl)phenyl]-;SCHEMBL11510708;WJTIFLYKIGCDQF-UHFFFAOYSA-N;DTXSID401232113;STK297710;AKOS000362603;MCULE-3007022149

Chemical Property of 2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide

Chemical Property:

• Melting Point: 143 - 144 °C
• PSA: 29.10000
• LogP: 3.37290
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 231.08709849
• Heavy Atom Count: 16
• Complexity: 242

Purity/Quality:

99% ^*data from raw suppliers

2-METHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)C(=O)NC1=CC=C(C=C1)C(F)(F)F

Technology Process of 2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide

There total 3 articles about 2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

Isobutyronitrile (78-82-0) + mesityl(4-(trifluoromethyl)phenyl)-λ3-iodanyl trifluoromethanesulfonate (1232133-62-8) → N-(4-(trifluoromethyl)phenyl)isobutyramide (1978-70-7)

Guidance literature:

With copper diacetate; In water; 1,2-dichloro-ethane; at 80 ℃; for 20h; Schlenk technique; Sealed tube;

Reference yield: 40.0%

Isobutyronitrile (78-82-0) + CF3O3S(1-)*C22H19F3I(1+) → N-(4-(trifluoromethyl)phenyl)isobutyramide (1978-70-7)

Guidance literature:

With water; copper diacetate; In 1,2-dichloro-ethane; at 80 ℃; for 20h;

DOI:10.1016/j.tetlet.2021.153048

Reference yield:

→ N-(4-(trifluoromethyl)phenyl)isobutyramide (1978-70-7)

Guidance literature:

/BRN= 2735880/;

upstream raw materials:

Isobutyronitrile

mesityl(4-(trifluoromethyl)phenyl)-λ³-iodanyl trifluoromethanesulfonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1978-70-7 Propanamide, 2-methyl-N-[4-(trifluoromethyl)phenyl]-

Send

Send

Metric Ton KG G Pound L ML

Send

Send