6-Chloro-2,3-dihydro-1h-indole

Base Information

• Chemical Name: 6-Chloro-2,3-dihydro-1h-indole
• CAS No.: 52537-00-5
• Molecular Formula: C8H8 Cl N
• Molecular Weight: 153.611
• Hs Code.: 2933990090
• NSC Number: 87628
• DSSTox Substance ID: DTXSID20293174
• Wikidata: Q82031808
• Mol file: 52537-00-5.mol

Synonyms:6-chloro-2,3-dihydro-1h-indole;52537-00-5;6-Chloroindoline;1H-Indole, 6-chloro-2,3-dihydro-;MFCD07371639;6-chloro-indoline;NSC87628;6-chloro-2,3-dihydroindole;SCHEMBL549646;DTXSID20293174;HSLNYVREDLDESE-UHFFFAOYSA-N;AMY42389;NSC-87628;AKOS006229895;SB37510;DS-14155;SY019160;BB 0260949;CS-0043962;FT-0715060;EN300-59997;F11859;A829131;Z926915320

Chemical Property of 6-Chloro-2,3-dihydro-1h-indole

Chemical Property:

• Vapor Pressure: 0.0218mmHg at 25°C
• Boiling Point: 250.3°C at 760 mmHg
• PKA: 4.32±0.20(Predicted)
• Flash Point: 105.2°C
• PSA: 12.03000
• Density: 1.214g/cm³
• LogP: 2.44600
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 153.0345270
• Heavy Atom Count: 10
• Complexity: 126

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloro-2,3-dihydro-1H-indole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNC2=C1C=CC(=C2)Cl

Technology Process of 6-Chloro-2,3-dihydro-1h-indole

There total 2 articles about 6-Chloro-2,3-dihydro-1h-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.2%

7-chloro-2,4-dihydro-2,1-benzothiazine 2,2-oxide (76653-03-7) → 6-chloroindole (17422-33-2) + 6-chloroindoline (52537-00-5)

Guidance literature:

at 650 ℃; Product distribution;

DOI:10.1021/ja00396a039

Reference yield: 62.6%

4-chloro-β-phenethylsulfonyl azide (54664-52-7) → 4-vinylbenzyl chloride (1073-67-2,24991-47-7) + 6-chloroindole (17422-33-2) + 6-chloroindoline (52537-00-5) + 4-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine (54664-55-0)

Guidance literature:

at 650 ℃; for 0.26h; Product distribution;

DOI:10.1021/ja00396a039

Reference yield: 100.0%

6-chloroindoline (52537-00-5) → 6-chloroindole (17422-33-2)

Guidance literature:

tris(triphenylphosphine)ruthenium(II) chloride; In toluene; for 6h; Rate constant; Mechanism; Heating;

DOI:10.1021/jo00289a036

upstream raw materials:

4-chloro-β-phenethylsulfonyl azide

7-chloro-2,4-dihydro-2,1-benzothiazine 2,2-oxide

Downstream raw materials:

6-chloroindole

1-indoline

C₂₁H₁₅ClF₃N₃O₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 52537-00-5 6-CHLORO-2,3-DIHYDRO-1H-INDOLE

Send

Send

Metric Ton KG G Pound L ML

Send

Send