Chloro(2,4,6-trimethylphenyl)silane

Base Information

• Chemical Name: Chloro(2,4,6-trimethylphenyl)silane
• CAS No.: 198883-34-0
• Molecular Formula: C9H13ClSi
• Molecular Weight: 184.741
• DSSTox Substance ID: DTXSID90772764
• Mol file: 198883-34-0.mol

Synonyms:Chloro(2,4,6-trimethylphenyl)silane;198883-34-0;mesitylchlorosilane;SCHEMBL3481737;DTXSID90772764

Chemical Property of Chloro(2,4,6-trimethylphenyl)silane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 182.0318546
• Heavy Atom Count: 11
• Complexity: 115

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)C)[Si]Cl)C

Technology Process of Chloro(2,4,6-trimethylphenyl)silane

There total 5 articles about Chloro(2,4,6-trimethylphenyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(2,4,6-trimethylphenyl)silane (120578-34-9) → chloro(mesityl)silane (198883-34-0)

Guidance literature:

With boron trichloride; In hexane; at 20 ℃; for 14h;

Reference yield:

2,4,6-trimethyl-phenyl-trimethoxysilane → chloro(mesityl)silane (198883-34-0)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / diethyl ether / 3 h / 0 - 23 °C

2: boron trichloride / dichloromethane; hexane / 0 - 23 °C

With lithium aluminium tetrahydride; boron trichloride; In diethyl ether; hexane; dichloromethane;

DOI:10.1021/acs.orglett.6b01223

Reference yield:

2,4,6-trimethylphenyl bromide (576-83-0) → chloro(mesityl)silane (198883-34-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: magnesium; hydrogenchloride; iodine / methanol; diethyl ether / Reflux

1.2: -5 - 23 °C

2.1: lithium aluminium tetrahydride / diethyl ether / 3 h / 0 - 23 °C

3.1: boron trichloride / dichloromethane; hexane / 0 - 23 °C

With hydrogenchloride; lithium aluminium tetrahydride; iodine; boron trichloride; magnesium; In methanol; diethyl ether; hexane; dichloromethane;

DOI:10.1021/acs.orglett.6b01223

upstream raw materials:

(2,4,6-trimethylphenyl)silane

2-mesitylmagnesium bromide

2,4,6-trimethylphenyl bromide

Downstream raw materials:

(2,6-bis(trifluoromethyl)phenyl)(mesityl)silane

(2,6-bis(trifluoromethyl)phenyl)(mesityl)silanediol

C₂₄H₃₅NOSi

C₂₆H₃₃NO₃Si