Propanoic acid, 3,3'-[[2-[(3-methoxy-3-oxopropoxy)methyl]-2-[[(phenylmethoxy)carbonyl] amino]-1,3-propanediyl]bis(oxy)]bis-, dimethyl ester

Base Information

• Chemical Name: Propanoic acid, 3,3'-[[2-[(3-methoxy-3-oxopropoxy)methyl]-2-[[(phenylmethoxy)carbonyl] amino]-1,3-propanediyl]bis(oxy)]bis-, dimethyl ester
• CAS No.: 200133-15-9
• Molecular Formula: C24H35NO11
• Molecular Weight: 513.542
• Mol file: 200133-15-9.mol

Synonyms:3-[2-Benzyloxycarbonylamino-3-(2-methoxycarbonyl-ethoxy)-2-(2-methoxycarbonyl-ethoxymethyl)-propoxy]-propionic acid methyl ester;

Chemical Property of Propanoic acid, 3,3'-[[2-[(3-methoxy-3-oxopropoxy)methyl]-2-[[(phenylmethoxy)carbonyl] amino]-1,3-propanediyl]bis(oxy)]bis-, dimethyl ester

Chemical Property:

• PSA: 144.92000
• LogP: 1.78160

Purity/Quality:

Methyl3-[3-(3-methoxy-3-oxopropoxy)-2-[(3-methoxy-3-oxopropoxy)methyl]-2-(phenylmethoxycarbonylamino)propoxy]propanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanoic acid, 3,3'-[[2-[(3-methoxy-3-oxopropoxy)methyl]-2-[[(phenylmethoxy)carbonyl] amino]-1,3-propanediyl]bis(oxy)]bis-, dimethyl ester

There total 2 articles about Propanoic acid, 3,3'-[[2-[(3-methoxy-3-oxopropoxy)methyl]-2-[[(phenylmethoxy)carbonyl] amino]-1,3-propanediyl]bis(oxy)]bis-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

benzyl chloroformate (501-53-1,94274-21-2) + tris[(carboxyethoxy)ethyl](amino)methane trimethyl ester (166047-75-2) → N-(Benzyloxycarbonyl)-tris[((methoxycarbonyl)ethoxy)methyl]aminomethane (200133-15-9)

Guidance literature:

With sodium hydroxide; sodium hydrogencarbonate; In water; at 0 ℃; for 1h;

DOI:10.1002/hlca.19970800721

Reference yield: 77.3%

→ N-(Benzyloxycarbonyl)-tris[((methoxycarbonyl)ethoxy)methyl]aminomethane (200133-15-9)

Guidance literature:

Reference yield: 99.0%

N-(Benzyloxycarbonyl)-tris[((methoxycarbonyl)ethoxy)methyl]aminomethane (200133-15-9) → benzyl N-tris[(2-carboxyethyloxy)methyl]methylcarbamate (200133-16-0)

Guidance literature:

With sodium hydroxide; In methanol; water; for 5h; Ambient temperature;

DOI:10.1002/hlca.19970800721

upstream raw materials:

benzyl chloroformate

tris[(carboxyethoxy)ethyl](amino)methane trimethyl ester

Downstream raw materials:

benzyl N-tris[(2-carboxyethyloxy)methyl]methylcarbamate

tris{[2-(tert-butoxycarbonyl)ethoxy]methyl}methylamine

di-tert-butyl 3,3'-((2-(((benzyloxy)carbonyl)amino)-2-((3-(tert-butoxy)-3-oxopropoxy)methyl)propane-1,3-diyl)bis(oxy))dipropionate