8-Methyl-3,4-dihydroquinolin-2(1H)-one

Base Information

Chemical Name:8-Methyl-3,4-dihydroquinolin-2(1H)-one
CAS No.:20151-47-7
Molecular Formula:C10H11NO
Molecular Weight:161.203
Hs Code.:2933790090
DSSTox Substance ID:DTXSID90516524
Nikkaji Number:J465.431E
Wikidata:Q82377992
Mol file:20151-47-7.mol

Synonyms:8-METHYL-3,4-DIHYDROQUINOLIN-2(1H)-ONE;20151-47-7;2(1H)-Quinolinone, 3,4-dihydro-8-methyl-;8-METHYL-3,4-DIHYDRO-1H-QUINOLIN-2-ONE;3,4-DIHYDRO-8-METHYL-2-QUINOLINONE;SCHEMBL434004;DTXSID90516524;AC5320;MFCD00464327;AKOS022451349;MB01240;8-methyl-3,4-dihydro-2(1h)quinolinone;BS-21954;SY021047;8-methyl-3, 4-dihydro-1H-quinolin-2-one;CS-0096484;3,4-DIHYDRO-8-METHYL-2(1H)-QUINOLINONE;A926101

Suppliers and Price of 8-Methyl-3,4-dihydroquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3,4-dihydro-8-methyl-2(1H)-Quinolinone 97.00%
1G
$ 2280.00

AccelPharmtech
3,4-dihydro-8-methyl-2(1H)-Quinolinone 97.00%
5G
$ 3900.00

Acrotein
3,4-Dihydro-8-methyl-2(1H)-quinolinone 97%
0.25g
$ 146.67

AK Scientific
8-Methyl-3,4-dihydroquinolin-2(1H)-one
5g
$ 721.00

Alichem
8-Methyl-3,4-dihydroquinolin-2(1H)-one
1g
$ 673.20

American Custom Chemicals Corporation
2(1H)-QUINOLINONE, 3,4-DIHYDRO-8-METHYL 95.00%
5MG
$ 500.85

Chemenu
8-Methyl-3,4-dihydroquinolin-2(1H)-one 95%
1g
$ 636.00

Crysdot
8-Methyl-3,4-dihydroquinolin-2(1H)-one 95+%
1g
$ 673.00

SynQuest Laboratories
8-Methyl-3,4-dihydroquinolin-2(1H)-one
5 g
$ 1098.00

TRC
3,4-Dihydro-8-methyl-2(1H)-quinolinone
1mg
$ 45.00

Total 10 raw suppliers

Chemical Property of 8-Methyl-3,4-dihydroquinolin-2(1H)-one

Chemical Property:

PSA：32.59000
LogP:1.96480
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:161.084063974
Heavy Atom Count:12
Complexity:190

Purity/Quality:

97% ^*data from raw suppliers

3,4-dihydro-8-methyl-2(1H)-Quinolinone 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)CCC(=O)N2

Technology Process of 8-Methyl-3,4-dihydroquinolin-2(1H)-one

There total 11 articles about 8-Methyl-3,4-dihydroquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 52601-70-4
8-methyl-1,2,3,4-tetrahydroquinoline

: 611-32-5
8-methylquinoline

: 20151-47-7
8-methyl-3,4-dihydroquinolin-2(1H)-one

: 8,8'-dimethyl-1,2,3,4-tetrahydro-2,3'-biquinoline

Guidance literature:: With glucose dehydrogenase; D-glucose; cytochrome P₄₅₀ enzyme CYP₁₀₂A₁ A₈₂M/F₈₇A/H₁₇₁L/Q₃₀₇H/N₃₁₉Y mutant; C₂₁H₂₅N₇O₁₇P₃^(3-)*2H⁽¹⁺⁾*Na⁽¹⁺⁾; In aq. phosphate buffer; ethanol; at 20 ℃; for 18h; pH=8.4; Catalytic behavior; Enzymatic reaction;
DOI:10.1002/anie.201904157

Reference yield: 22.0%

: C₁₉H₁₅F₆NO₃

: 20151-46-6
5-methyl-1,2,3,4-tetrahydroquinolin-2-one

: 20151-47-7
8-methyl-3,4-dihydroquinolin-2(1H)-one

Guidance literature:: With Ir(CF₃ppy)₃; In acetonitrile; at 25 ℃; for 12h; Inert atmosphere; Irradiation;
DOI:10.1002/anie.202108775

Reference yield: 7.0%

: 52601-70-4
8-methyl-1,2,3,4-tetrahydroquinoline

: 611-32-5
8-methylquinoline

: 20151-47-7
8-methyl-3,4-dihydroquinolin-2(1H)-one

: 8,8'-dimethyl-1,2,3,4-tetrahydro-2,3'-biquinoline

: 6-hydroxy-8-methyl-1,2,3,4-tetrahydroquinoline

Guidance literature:: With glucose dehydrogenase; D-glucose; cytochrome P₄₅₀ enzyme CYP₁₀₂A₁ A₇₄G/F₈₇V/L₁₈₈Q/A₂₆₄G mutant; C₂₁H₂₅N₇O₁₇P₃^(3-)*2H⁽¹⁺⁾*Na⁽¹⁺⁾; In aq. phosphate buffer; ethanol; at 20 ℃; for 8h; pH=8.4; Reagent/catalyst; Catalytic behavior; Enzymatic reaction;
DOI:10.1002/anie.201904157