2-Pyridinecarboxamide, N-(2-mercaptophenyl)-

Base Information

• Chemical Name: 2-Pyridinecarboxamide, N-(2-mercaptophenyl)-
• CAS No.: 203192-27-2
• Molecular Formula: C12H10N2OS
• Molecular Weight: 230.29
• Mol file: 203192-27-2.mol

Synonyms:

Chemical Property of 2-Pyridinecarboxamide, N-(2-mercaptophenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Pyridinecarboxamide, N-(2-mercaptophenyl)-

There total 2 articles about 2-Pyridinecarboxamide, N-(2-mercaptophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

pyridine-2-carbonyl chloride (29745-44-6) + 2-amino-benzenethiol (137-07-5) → N-(2-mercaptophenyl)-2'-pyridinecarboxamide (203192-27-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1081/SCC-120020209

Reference yield:

→ N-(2-mercaptophenyl)-2'-pyridinecarboxamide (203192-27-2)

Guidance literature:

Pyridin-2-carbonsaeure, 1.) Oxalylchlorid, 2.) o-Aminothiophenol (Nebenprod.);

Reference yield: 41.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + bis(acetylacetonato)dioxidomolybdenum(VI) + tert.-butyl lithium (594-19-4) + N-(2-mercaptophenyl)-2'-pyridinecarboxamide (203192-27-2) → MoO2(N-(2-mercaptophenyl)-2'-picolinamide-2H)*2THF + ([Li(tetrahydrofuran)2(acetate)]2[(acetylacetonate)Mo(V)O(μ-O)2(μ-acetate)Mo(V)O])2Na2([Mo8O26]][Li(tetrahidrofuran)3]2)

Guidance literature:

In tetrahydrofuran; hexane; all manipulations under Schlenk conditions; N compd. dissolved in abs. THF and cooled in mixt. of EtOH and liquid N2, soln. of Li compd. in hexane added dropwise under stirring, allowed to warm to room temp., stirredfor 1 h, soln. of Mo compd. in THF; added dropwise, stirred overnight, filtered, washed with THF; elem. anal.; filtrate concd., allowed to stand at 4°C for couple of wk and Li-Mo compd. obtained;

DOI:10.1016/j.inoche.2006.04.014

upstream raw materials:

pyridine-2-carbonyl chloride

2-amino-benzenethiol