tert-Butyl 4-(3-{[(4-methylbenzene)sulfonyl]oxy}propyl)piperidine-1-carboxylate

Base Information

• Chemical Name: tert-Butyl 4-(3-{[(4-methylbenzene)sulfonyl]oxy}propyl)piperidine-1-carboxylate
• CAS No.: 203306-85-8
• Molecular Formula: C20H31NO5S
• Molecular Weight: 397.536
• DSSTox Substance ID: DTXSID701127981
• Mol file: 203306-85-8.mol

Synonyms:203306-85-8;tert-Butyl 4-(3-{[(4-methylbenzene)sulfonyl]oxy}propyl)piperidine-1-carboxylate;tert-butyl 4-[3-(4-methylphenyl)sulfonyloxypropyl]piperidine-1-carboxylate;SCHEMBL8651411;DTXSID701127981;BS-32072;1,1-Dimethylethyl 4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1-piperidinecarboxylate;1N-tert-BUTOXYCARBONYL-4(R/S)-[3-(4-TOLUENESULFONYLOXY)PROPYL]PIPERIDINE;tert-Butyl4-(3-{[(4-methylbenzene)sulfonyl]oxy}propyl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-,1,1-dimethylethyl ester

Chemical Property of tert-Butyl 4-(3-{[(4-methylbenzene)sulfonyl]oxy}propyl)piperidine-1-carboxylate

Chemical Property:

• Boiling Point: 510.6±23.0 °C(Predicted)
• PKA: -1.37±0.40(Predicted)
• PSA: 81.29000
• Density: 1.143±0.06 g/cm3(Predicted)
• LogP: 5.14630
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 397.19229426
• Heavy Atom Count: 27
• Complexity: 562

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCCCC2CCN(CC2)C(=O)OC(C)(C)C

Technology Process of tert-Butyl 4-(3-{[(4-methylbenzene)sulfonyl]oxy}propyl)piperidine-1-carboxylate

There total 2 articles about tert-Butyl 4-(3-{[(4-methylbenzene)sulfonyl]oxy}propyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

p-toluenesulfonyl chloride (98-59-9) + N-Boc-piperidin-4-yl-propanol (156185-63-6) → tert-butyl 4-[3-(p-tolylsulfonyloxy)propyl]piperidine-1-carboxylate (203306-85-8)

Guidance literature:

In pyridine; methanol; dichloromethane;

Reference yield:

→ tert-butyl 4-[3-(p-tolylsulfonyloxy)propyl]piperidine-1-carboxylate (203306-85-8)

Guidance literature:

Reference yield: 96.0%

pyridine N-oxide (694-59-7) + tert-butyl 4-[3-(p-tolylsulfonyloxy)propyl]piperidine-1-carboxylate (203306-85-8) → 1-(3-(1-(tert-butoxycarbonyl)piperidin-4-yl)propoxy)pyridin-1-ium 4-methylbenzenesulfonate

Guidance literature:

In acetonitrile; at 60 - 70 ℃;

DOI:10.1002/anie.201809879

upstream raw materials:

p-toluenesulfonyl chloride

N-Boc-piperidin-4-yl-propanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 203306-85-8 1N-tert-BUTOXYCARBONYL-4(R/S)-[3-(4-TOLUENESULFONYLOXY)PROPYL]PIPERIDINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send