8-chloro-2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one

Base Information

Chemical Name:8-chloro-2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one
CAS No.:204511-46-6
Molecular Formula:C₁₆H₁₀ClN₃O
Molecular Weight:295.728
Hs Code.:
DSSTox Substance ID:DTXSID50438334
Nikkaji Number:J928.803A
Wikidata:Q82254041
Pharos Ligand ID:NV74UG89YRTV
ChEMBL ID:CHEMBL104478

Synonyms:204511-46-6;CHEMBL104478;8-Chloro-2-phenyl-2H-pyrazolo[3,4-c]quinolin-4(5H)-one;8-chloro-2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one;DTXSID50438334;BDBM50091120;2-Phenyl-8-chloro-2H-pyrazolo[3,4-c]quinolin-4(5H)-one;8-Chloro-2-phenyl-2,5-dihydro-pyrazolo[3,4-c]quinolin-4-one

Suppliers and Price of 8-chloro-2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 8-chloro-2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:295.0512396
Heavy Atom Count:21
Complexity:412

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C=C3C4=C(C=CC(=C4)Cl)NC(=O)C3=N2

Technology Process of 8-chloro-2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one

There total 1 articles about 8-chloro-2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17422-32-1
5-chloro-1H-indole

: 204511-46-6
8-Chloro-2-phenyl-2,5-dihydro-pyrazolo[3,4-c]quinolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / pyridine / diethyl ether / 1) 0 deg C, 1 h, 2) r.t., 5 h

2: 64 percent / glac. HOAc / ethanol / 3 h / Heating

With pyridine; acetic acid; In diethyl ether; ethanol;
DOI:10.1002/ardp.19973301205

Reference yield:

: 204511-46-6
8-Chloro-2-phenyl-2,5-dihydro-pyrazolo[3,4-c]quinolin-4-one

: 8-chloro-2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: PCl₅; POCl₃ / 2 h / Heating

2: 80 percent / NH₃ / ethanol / 120 °C

With phosphorus pentachloride; ammonia; trichlorophosphate; In ethanol; 1: Chlorination / 2: Substitution;
DOI:10.1021/jm000936i