Bicyclo[2.2.2]octan-2-amine

Base Information

• Chemical Name: Bicyclo[2.2.2]octan-2-amine
• CAS No.: 20643-57-6
• Molecular Formula: C8H15N
• Molecular Weight: 125.12
• Mol file: 20643-57-6.mol

Synonyms:Bicyclo[2.2.2]octan-3-amine;

Chemical Property of Bicyclo[2.2.2]octan-2-amine

Chemical Property:

• Boiling Point: 183.874 °C at 760 mmHg
• Flash Point: 63.449 °C
• Density: 0.959 g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bicyclo[2.2.2]octan-2-amine

There total 6 articles about Bicyclo[2.2.2]octan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-bicyclo[2.2.2]oct-2-yl-phthalimide → 2-Amino-bicyclo<2.2.2>octan (20643-57-6,163580-78-7)

Guidance literature:

With hydrazine hydrate; In ethanol;

DOI:10.1002/hlca.19670500839

Reference yield:

α-Chlorbicyclo<2,2,2>octanonoxim (13380-76-2) → 2-Amino-bicyclo<2.2.2>octan (20643-57-6,163580-78-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield:

norbornene (931-64-6) → 2-Amino-bicyclo<2.2.2>octan (20643-57-6,163580-78-7)

Guidance literature:

Multi-step reaction with 2 steps

1: NOCl, HCl / diethyl ether

2: LiAlH₄ / diethyl ether

With hydrogenchloride; lithium aluminium tetrahydride; nitrosylchloride; In diethyl ether;

upstream raw materials:

bicyclo<2.2.2>octanone oxime

α-Chlorbicyclo<2,2,2>octanonoxim

norbornene