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2-Ammonioethanesulfonate

Base Information Edit
  • Chemical Name:2-Ammonioethanesulfonate
  • CAS No.:107-35-7
  • Molecular Formula:C2H7NO3S
  • Molecular Weight:125.148
  • Hs Code.:29211980
  • Mol file:107-35-7.mol
2-Ammonioethanesulfonate

Synonyms:2-ammonioethanesulfonate;2-azaniumylethanesulfonate;aminoetylsulphonic acid;ethylaminesulphonic acid;2-amino-ethanesulfonic acid;taurine zwitterion;2-azaniumylethane-1-sulfonate;CHEBI:507393;AKOS025117017;InChI=1/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6

Suppliers and Price of 2-Ammonioethanesulfonate
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Taurine
  • 100g
  • $ 134.00
  • TRC
  • Taurine
  • 50mg
  • $ 85.00
  • Tocris
  • Taurine
  • 1G
  • $ 61.00
  • TCI Chemical
  • 2-Aminoethanesulfonic Acid >98.0%(T)
  • 25g
  • $ 14.00
  • TCI Chemical
  • 2-Aminoethanesulfonic Acid >98.0%(T)
  • 500g
  • $ 37.00
  • Sigma-Aldrich
  • Taurine PharmaGrade, Ajinomoto, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture
  • 1kg
  • $ 705.00
  • Sigma-Aldrich
  • Taurine cell culture tested, meets USP testing specifications
  • 1kg
  • $ 620.00
  • Sigma-Aldrich
  • Taurine ≥99%
  • 1kg
  • $ 431.00
  • Sigma-Aldrich
  • Taurine United States Pharmacopeia (USP) Reference Standard
  • 100mg
  • $ 315.00
  • Sigma-Aldrich
  • Taurine ≥98%, FG
  • 10 kg
  • $ 294.00
Total 387 raw suppliers
Chemical Property of 2-Ammonioethanesulfonate Edit
Chemical Property:
  • Appearance/Colour:White crystalline powder 
  • Melting Point:>300 °C(lit.) 
  • Refractive Index:1.515 
  • PKA:1.5(at 25℃) 
  • PSA:88.77000 
  • Density:1.494 g/cm3 
  • LogP:0.61400 
  • Storage Temp.:2-8°C 
  • Solubility.:H2O: 0.5 M at 20 °C, clear, colorless 
  • Water Solubility.:5-10 g/100 mL at 23.5 ºC 
  • XLogP3:-4.2
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:1
  • Exact Mass:125.01466426
  • Heavy Atom Count:7
  • Complexity:107
Purity/Quality:

99%, *data from raw suppliers

Taurine *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36-24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:C(CS(=O)(=O)[O-])[NH3+]
  • Description Taurine is a sulfur-containing amino acid with multiple physiological functions, including the maintenance of mitochondrial health.
    While known as an antioxidant, its underlying mechanism is unclear as it is not a radical scavenger.
  • Chemical Composition and Properties Non-Essential Amino Acid: Taurine is a non-essential amino acid that does not participate in protein synthesis due to the absence of a carboxyl group.
    Abundance: It is abundant in various mammalian tissues, especially in electrically excitable tissues like the heart and brain.
    Water-Soluble: Taurine exhibits strong water-soluble and poor lipophilic properties.
  • Historical Background Discovery: Taurine was first isolated from ox bile by Friedrich Tiedemann and Leopold Gmelin in 1827.
    Naming: Initially named "Gallen - Asparagin," it was later named "taurus" after the Latin Bos taurus, and finally referred to as "taurine" in 1838 by von H. Demarcay.
  • Metabolic and Physiological Functions Derivation and Abundance: Taurine can be derived from cysteine metabolism and accounts for a significant portion of the free amino acid pool.
    Sources: Dietary sources of taurine include animal proteins.
    Benefits: Taurine plays roles in glucose and lipid regulation, energy metabolism, anti-inflammatory modulation, and antioxidant actions.
    Ergogenic Aid: Taurine has been used as a potential ergogenic aid to enhance athletic performance.
  • Absorption and Excretion Absorption: Taurine absorption occurs mainly in the gastrointestinal tract, with improved bioavailability on an empty stomach.
    Excretion: Kidneys regulate plasma taurine concentrations through urine excretion.
  • Role in Fat Metabolism Modulation: Taurine modulates fat metabolism, increasing lipolysis and altering fuel utilization and metabolic efficiency during exercise.
    Mitochondrial Function: It inhibits oxidative stress by improving mitochondrial function and promoting mitochondrial biogenesis.
Technology Process of 2-Ammonioethanesulfonate

There total 92 articles about 2-Ammonioethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogen; at 55 ℃; under 22502.3 Torr; Temperature; Pressure; Reagent/catalyst; Inert atmosphere;
Guidance literature:
With ammonium hydroxide; at 150 ℃; for 0.0833333h; under 45004.5 Torr; Temperature; Time; Pressure; Microwave irradiation;

Reference yield: 98.4%

Guidance literature:
With 2,2,6,6-tetramethyl-piperidine; In water; at 140 ℃; for 0.166667h; under 3000.3 Torr; Reagent/catalyst; Temperature; Pressure;
Refernces Edit

Analyte-induced aggregation of conjugated polyelectrolytes: Role of the charged moieties and its sensing application

10.1039/c002188a

The study investigates the role of charged moieties in the aggregation of cationic conjugated polyelectrolytes (CPEs) and their application in colorimetric sensing of taurine, a sulfur-containing semiessential amino acid. The researchers utilized a cationic polythiophene derivative, poly(3-(4-methyl-30-thienyloxy)propyltrimethylammonium) (PMTPA), which is sensitive to external stimuli and can act as a colorimetric probe for detecting various bioanalytes. The study focused on the interaction between PMTPA and model analytes such as 2-naphthalenesulfonic acid (NSA), 2-naphthalenecarboxylic acid (NCA), and 2-naphthylphosphoric acid (NPA) to understand how these chemicals influence the aggregation of PMTPA. The purpose of these chemicals was to examine the hard-soft acid-base principle in the context of electrostatic interactions and to develop a method for detecting taurine. The researchers also used o-phthalaldehyde (OPA) to premodify taurine, converting it into a sulfonate-containing derivative (PI-taurine), which enhances its interaction with PMTPA and allows for colorimetric detection. The study demonstrated that PMTPA could selectively respond to taurine in aqueous solutions, leading to a color change and providing a simple means for visual detection, which has potential applications in sensing small bioanions.

Synthesis and biological evaluation of novel irreversible serine protease inhibitors using amino acid based sulfonyl fluorides as an electrophilic trap

10.1016/j.bmc.2011.02.014

The researchers synthesized a series of substituted taurine sulfonyl fluorides derived from taurine or protected amino acids, using reagents such as KF/18-crown-6 and DAST for the synthesis of sulfonyl fluorides. The potency of these inhibitors was evaluated through various enzyme assays, leading to binding affinities up to 22 μM. The conclusions drawn from the study indicate that these sulfonyl fluorides are capable of irreversible competitive inhibition of serine proteases, with affinities dependent on the side chain of the inhibitor. The best binding affinity was observed for the phenylalanine-derived sulfonyl fluoride, which was comparable to the known potent inhibitor PMSF.

The first synthesis of optically active 1-substituted taurines

10.1002/hc.20133

The research aims to synthesize optically active 1-substituted taurines, which are important sulfur analogues of naturally occurring amino acids. These compounds and their N-benzyloxycarbonyl-protected derivatives were synthesized from optically active β-amino secondary alcohols through a three-step process involving N-protection with benzyl chloroformate, substitution with thiolacetic acid under Mitsunobu conditions, and oxidation with performic acid. The study concludes that optically active 1-substituted taurines can be successfully synthesized from the corresponding β-amino secondary alcohols, providing a new method for preparing these compounds. The synthesized taurines could serve as structural analogues for studying physiological processes involving naturally occurring 2-substituted 2-aminoethanesulfonic acids.

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