2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine

Base Information

Chemical Name:2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine
CAS No.:206550-70-1
Molecular Formula:C13H20ClNO
Molecular Weight:241.761
Hs Code.:
DSSTox Substance ID:DTXSID70500300
Wikidata:Q82351781

Synonyms:206550-70-1;2-(4-(Chloromethyl)phenoxy)-N,N-diethylethanamine;2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine;SCHEMBL6932789;DTXSID70500300;SXRGONXLOGEUEJ-UHFFFAOYSA-N;(2-(4chloromethyl-phenoxy)ethyl]diethylamine;(2-(4-chloromethyl-phenoxy)ethyl]diethylamine;[2-(4-chloromethyl-phenoxy)-ethyl]diethylamine;[2-(4-chloromethyl-phenoxy)ethyl]-diethylamine;[2-(4-chloromethyl-phenoxy)-ethyl]-diethylamine

Suppliers and Price of 2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:241.1233420
Heavy Atom Count:16
Complexity:165

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCOC1=CC=C(C=C1)CCl

Technology Process of 2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine

There total 4 articles about 2-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 46745-36-2
(4-(2-(diethylamino)ethoxy)phenyl)methan-1-ol

: 206550-70-1
4-(2-N,N-diethyl amino-ethoxy)-benzyl chloride

Guidance literature:: (4-(2-(diethylamino)ethoxy)phenyl)methan-1-ol; With hydrogenchloride; In tetrahydrofuran; at 0 ℃;

With thionyl chloride; In tetrahydrofuran; at 50 ℃;
DOI:10.1016/j.bmcl.2005.03.111

Reference yield:

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 206550-70-1
4-(2-N,N-diethyl amino-ethoxy)-benzyl chloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: K₂CO₃ / dimethylformamide / 120 °C

2.1: NaBH₄ / methanol / 20 °C

3.1: tetrahydrofuran / Heating

4.1: HCl (gas) / tetrahydrofuran / 0 °C

4.2: SOCl₂ / tetrahydrofuran / 50 °C

With hydrogenchloride; sodium tetrahydroborate; potassium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.03.111

Reference yield:

: 52191-15-8
4-(2-bromoethyloxy)benzaldehyde

: 206550-70-1
4-(2-N,N-diethyl amino-ethoxy)-benzyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaBH₄ / methanol / 20 °C

2.1: tetrahydrofuran / Heating

3.1: HCl (gas) / tetrahydrofuran / 0 °C

3.2: SOCl₂ / tetrahydrofuran / 50 °C

With hydrogenchloride; sodium tetrahydroborate; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2005.03.111