1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-[(4-methoxyphenyl)methyl]-

Base Information

Chemical Name:1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-[(4-methoxyphenyl)methyl]-
CAS No.:206977-00-6
Molecular Formula:C16H15NO3
Molecular Weight:269.3
Hs Code.:
DSSTox Substance ID:DTXSID50408532
Nikkaji Number:J946.394A

Synonyms:206977-00-6;3-hydroxy-2-[(4-methoxyphenyl)methyl]-3H-isoindol-1-one;1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-[(4-methoxyphenyl)methyl]-;SCHEMBL2644150;DTXSID50408532;AKOS037478346

Suppliers and Price of 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-[(4-methoxyphenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-[(4-methoxyphenyl)methyl]-

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:269.10519334
Heavy Atom Count:20
Complexity:352

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CN2C(C3=CC=CC=C3C2=O)O

Technology Process of 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-[(4-methoxyphenyl)methyl]-

There total 1 articles about 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-2-[(4-methoxyphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 21244-24-6
2-[(4-methoxyphenyl)methyl]-1H-isoindole-1,3(2H)-dione

: 206977-00-6
3-hydroxy-2-(4-methoxybenzyl)-isoindolin-1-one

Guidance literature:: With sodium tetrahydroborate; In methanol; at -5 - 0 ℃;
DOI:10.1021/jo062077x

Reference yield: 93.0%

: 108-24-7
acetic anhydride

: 206977-00-6
3-hydroxy-2-(4-methoxybenzyl)-isoindolin-1-one

: 929206-60-0
3-acetoxy-2-(4-methoxybenzyl)-isoindolin-1-one

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1021/jo062077x

Reference yield: 92.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 206977-00-6
3-hydroxy-2-(4-methoxybenzyl)-isoindolin-1-one

: 3-(dimethylamino)-2-(4-methoxybenzyl)isoindolin-1-one

Guidance literature:: With copper(l) iodide; phenylboronic acid; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 17h;
DOI:10.1007/s12039-018-1474-8