Naphthol AS-MX phosphate

Base Information

• Chemical Name: Naphthol AS-MX phosphate
• CAS No.: 1596-56-1
• Molecular Formula: C₁₉H₁₈NO₅P
• Molecular Weight: 371.329
• European Community (EC) Number: 216-480-1
• DSSTox Substance ID: DTXSID60166696
• Nikkaji Number: J7.523J
• Wikidata: Q22668731
• Mol file: 1596-56-1.mol

Synonyms:naphthol AS-MX phosphate;naphthol AS-MX phosphate, sodium salt

Chemical Property of Naphthol AS-MX phosphate

Chemical Property:

• Appearance/Colour: cream-colored powder
• Melting Point: 189-190 °C
• Refractive Index: 1.692
• PKA: 0.80±0.30(Predicted)
• PSA: 105.67000
• Density: 1.419 g/cm³
• LogP: 4.25340
• Storage Temp.: 2-8°C
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 371.09225967
• Heavy Atom Count: 26
• Complexity: 550

Purity/Quality:

97% ^*data from raw suppliers

Naphthol AS-MX phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)NC(=O)C2=CC3=CC=CC=C3C=C2OP(=O)(O)O)C
• Uses: Naphthol AS-MX phosphate has been used as:a substrate for alkaline phosphatase in human osteoblastsmouse embryonic stem cell (mESC) coronal plane sections for fluorescence staining and analysis

Technology Process of Naphthol AS-MX phosphate

There total 3 articles about Naphthol AS-MX phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxy-N-2',4'-(dimethylphenyl)-2-naphthalenecarboxamide (92-75-1) → naphthol AS-MX phosphate (1596-56-1)

Guidance literature:

With phosphorus pentachloride; In 1,4-dioxane; at 50 ℃; for 1h;

DOI:10.1021/ac00080a022

Reference yield:

2,4-Xylidine (95-68-1) → naphthol AS-MX phosphate (1596-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) PCl₃ / 1) xylene, 80 deg C, 10 min; 2) xylene, reflux, 2 h

2: PCl₅ / dioxane / 1 h / 50 °C

With phosphorus pentachloride; phosphorus trichloride; In 1,4-dioxane;

DOI:10.1021/ac00080a022

Reference yield:

3-Hydroxy-2-naphthoic acid (92-70-6) → naphthol AS-MX phosphate (1596-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) PCl₃ / 1) xylene, 80 deg C, 10 min; 2) xylene, reflux, 2 h

2: PCl₅ / dioxane / 1 h / 50 °C

With phosphorus pentachloride; phosphorus trichloride; In 1,4-dioxane;

DOI:10.1021/ac00080a022

upstream raw materials:

3-hydroxy-N-2',4'-(dimethylphenyl)-2-naphthalenecarboxamide

2,4-Xylidine

3-Hydroxy-2-naphthoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1596-56-1 NAPHTHOL AS-MX PHOSPHATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send