2-(2-phenylethyl)-1H-isoindole-1,3(2H)-dione

Base Information

• Chemical Name: 2-(2-phenylethyl)-1H-isoindole-1,3(2H)-dione
• CAS No.: 7501-05-5
• Molecular Formula: C16H13 N O2
• Molecular Weight: 251.285
• Mol file: 7501-05-5.mol

Synonyms:Phthalimide,N-phenethyl- (8CI); 2-(2-Phenylethyl)-1H-isoindole-1,3(2H)-dione;2-(2-Phenylethyl)isoindole-1,3(2H)-dione; 2-Phenethylisoindole-1,3-dione;N-(2-Phenylethyl)phthalimide; N-Phenethylphthalimide; NSC 408070

Chemical Property of 2-(2-phenylethyl)-1H-isoindole-1,3(2H)-dione

Chemical Property:

• Vapor Pressure: 7.29E-07mmHg at 25°C
• Boiling Point: 407.9°Cat760mmHg
• Flash Point: 184.1°C
• Density: 1.251g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-phenylethyl)-1H-isoindole-1,3(2H)-dione

There total 41 articles about 2-(2-phenylethyl)-1H-isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

phthalic anhydride (85-44-9) + phenethylamine (64-04-0) → N-(2-phenylethyl)phthalimide (7501-05-5)

Guidance literature:

Heating;

DOI:10.1002/(SICI)1099-1344(199801)41:1<53::AID-JLCR53>3.0.CO;2-K

Reference yield: 100.0%

2,3-dihydro-3-hydroxy-2-(2-phenylethyl)-1H-isoindol-1-one (17416-58-9) → N-(2-phenylethyl)phthalimide (7501-05-5)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In acetonitrile; at 80 ℃; for 10h; Reagent/catalyst; Solvent;

DOI:10.3390/molecules27020548

Reference yield: 99.0%

phthalimide (136918-14-4,85-41-6) + phenethylamine (64-04-0) → N-(2-phenylethyl)phthalimide (7501-05-5)

Guidance literature:

With triethylamine; 3-diphenyloxyphosphinyl-2-oxazolidinone; In acetonitrile; at 40 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2006.12.003

upstream raw materials:

phthalic anhydride

phenethylamine

potassium phtalimide

1-phenyl-2-bromoethane

Downstream raw materials:

2-(isoquinolin-1-yl)benzoic acid

N-<2-(4-nitrophenyl)ethyl>phthalimide

2-phenethyl-(3ar,7ac)-octahydro-isoindole

2,3-dihydro-3-hydroxy-2-(2-phenylethyl)-1H-isoindol-1-one