3-Amino-N-tert-butylpropionamide hydrochloride

Base Information

• Chemical Name: 3-Amino-N-tert-butylpropionamide hydrochloride
• CAS No.: 209467-48-1
• Molecular Formula: C7H16N2O
• Molecular Weight: 180.67600
• Hs Code.: 2924199090
• Mol file: 209467-48-1.mol

Synonyms:3-amino-N-tert-butylpropanamide,hydrochloride;

Chemical Property of 3-Amino-N-tert-butylpropionamide hydrochloride

Chemical Property:

• PSA: 55.12000
• LogP: 2.14310
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

3-amino-N-tert-butylpropanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Amino-N-tert-butylpropionamide hydrochloride

There total 2 articles about 3-Amino-N-tert-butylpropionamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2-tert-butylcarbamoyl-ethyl)-carbamic acid tert-butyl ester (847789-44-0) → 3-amino-N-(tert-butyl)propanamide (209467-48-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.333333h;

Reference yield: 94.0%

C15H22N2O3 → 3-amino-N-(tert-butyl)propanamide (209467-48-1)

Guidance literature:

With 15 wt% palladium on carbon; hydrogen; In methanol; at 25 ℃; for 16h; under 3800.26 Torr;

DOI:10.3390/molecules24091814

Reference yield:

3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) + 3-amino-N-(tert-butyl)propanamide (209467-48-1) → N-(tert-butyl)-3-((3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propanamide

Guidance literature:

In methanol; at 50 ℃; for 3h;

DOI:10.3390/molecules24091814

upstream raw materials:

(2-tert-butylcarbamoyl-ethyl)-carbamic acid tert-butyl ester

Downstream raw materials:

3-{N^α-[6-({N-[2-(benzyloxycarbonylamino)ethyl]-N-(benzyloxycarbonyl)amino}methyl)-2-pyridylcarbonyl]-L-histidinylamino}-N-t-butylpropionamide

NVS-PI₃-4

Refernces

• 1、 Zwettler, Niklas,Ehweiner, Madeleine A.,Schachner, J?rg A.,Dupé, Antoine,Belaj, Ferdinand,M?sch-Zanetti, Nadia C.. "Dioxygen activation with molybdenum complexes bearing amide-functionalized iminophenolate ligands". . . Retrieved 2019/05/24.