6-([1,1'-Biphenyl]-4-yl)-4-methylpyridazin-3(2H)-one

Base Information

Chemical Name:6-([1,1'-Biphenyl]-4-yl)-4-methylpyridazin-3(2H)-one
CAS No.:21004-63-7
Molecular Formula:C17H14N2O
Molecular Weight:262.311
Hs Code.:
DSSTox Substance ID:DTXSID10458058
Wikidata:Q82281188

Synonyms:21004-63-7;6-([1,1'-Biphenyl]-4-yl)-4-methylpyridazin-3(2H)-one;5-methyl-3-(4-phenylphenyl)-1H-pyridazin-6-one;SCHEMBL11396912;DTXSID10458058

Suppliers and Price of 6-([1,1'-Biphenyl]-4-yl)-4-methylpyridazin-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 6-([1,1'-Biphenyl]-4-yl)-4-methylpyridazin-3(2H)-one

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:262.110613074
Heavy Atom Count:20
Complexity:424

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NNC1=O)C2=CC=C(C=C2)C3=CC=CC=C3

Technology Process of 6-([1,1'-Biphenyl]-4-yl)-4-methylpyridazin-3(2H)-one

There total 5 articles about 6-([1,1'-Biphenyl]-4-yl)-4-methylpyridazin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 845961-37-7
4-Biphenyl-4-yl-2-methylene-4-oxo-butyric acid methyl ester

: 21004-63-7
6-biphenyl-4-yl-4-methyl-2H-pyridazin-3-one

Guidance literature:: With sodium acetate; hydrazine hydrate; In methanol; Heating;

Reference yield:

: 92-52-4,1594-86-1
biphenyl

: 21004-63-7
6-biphenyl-4-yl-4-methyl-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: 66 percent / aluminium chloride / nitrobenzene / 4 h / 20 °C

2: 73 percent / potassium carbonate / acetone / Heating

3: 76 percent / hydrazine hydrate; sodium acetate / methanol / Heating

With aluminium trichloride; sodium acetate; potassium carbonate; hydrazine hydrate; In methanol; nitrobenzene; acetone; 1: Friedel-Crafts acylation;

Reference yield:

: 19340-35-3
4-(4-biphenylyl)-4-oxo-2-methyl butanoic acid

: 21004-63-7
6-biphenyl-4-yl-4-methyl-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / potassium carbonate / acetone / Heating

2: 76 percent / hydrazine hydrate; sodium acetate / methanol / Heating

With sodium acetate; potassium carbonate; hydrazine hydrate; In methanol; acetone;