Carbamic acid, 3-cyclohexen-1-yl-, phenylmethyl ester

Base Information

• Chemical Name: Carbamic acid, 3-cyclohexen-1-yl-, phenylmethyl ester
• CAS No.: 210574-45-1
• Molecular Formula: C14H17NO2
• Molecular Weight: 231.294
• Mol file: 210574-45-1.mol

Synonyms:

Chemical Property of Carbamic acid, 3-cyclohexen-1-yl-, phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, 3-cyclohexen-1-yl-, phenylmethyl ester

There total 10 articles about Carbamic acid, 3-cyclohexen-1-yl-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-benzyloxycarbonylaminoocta-1,7-diene → benzyl N-(cyclohex-3-en-1-yl)carbamate (210574-45-1)

Guidance literature:

Grubbs catalyst first generation; In dichloromethane; at 23 ℃; for 24h;

DOI:10.1055/s-1998-1789

Reference yield: 95.0%

1,2,5,6-tetrahydrobenzoic acid (4771-80-6) + benzyloxycarbonyl azide (3422-03-5) → benzyl N-(cyclohex-3-en-1-yl)carbamate (210574-45-1)

Guidance literature:

With dmap; copper diacetate; In acetonitrile; at 80 ℃; for 3h; Schlenk technique; Sealed tube;

DOI:10.1002/anie.202010974

Reference yield: 81.0%

1,2,5,6-tetrahydrobenzoic acid (4771-80-6) + benzyl alcohol (100-51-6,185532-71-2) → benzyl N-(cyclohex-3-en-1-yl)carbamate (210574-45-1)

Guidance literature:

1,2,5,6-tetrahydrobenzoic acid; With diphenylphosphoranyl azide; triethylamine; In toluene; at 25 - 110 ℃; for 4h; Inert atmosphere;

benzyl alcohol; In toluene; at 110 ℃; for 12h;

upstream raw materials:

1,2,5,6-tetrahydrobenzoic acid

benzyl alcohol

4-pentenal

O-benzyl carbamate

Downstream raw materials:

(1β,3α,4α)-benzyl N-(3,4-dihydroxy-1-cyclohexyl)carbamate

3-Cyclohexenyl-1-amine