5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide

Base Information

Chemical Name:5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide
CAS No.:21254-07-9
Molecular Formula:C10H16N4O
Molecular Weight:208.263
Hs Code.:2933199090
DSSTox Substance ID:DTXSID00591766
Wikidata:Q82485630
Mol file:21254-07-9.mol

Synonyms:5-AMINO-1-CYCLOHEXYL-1H-PYRAZOLE-4-CARBOXAMIDE;21254-07-9;5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxylic Acid Amide;SCHEMBL2078467;DTXSID00591766;NEMOBXGSUJGZAF-UHFFFAOYSA-N;AM9854

Suppliers and Price of 5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide 95+%
1g
$ 673.00

Alichem
5-Amino-1-cyclohexyl-1h-pyrazole-4-carboxamide
1g
$ 751.80

Total 1 raw suppliers

Chemical Property of 5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide

Chemical Property:

Melting Point:267-268 °C
Boiling Point:425.2±25.0 °C(Predicted)
PKA:15.23±0.50(Predicted)
PSA：87.92000
Density:1.45±0.1 g/cm3(Predicted)
LogP:2.53480
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:208.13241115
Heavy Atom Count:15
Complexity:240

Purity/Quality:: 5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)N2C(=C(C=N2)C(=O)N)N

Technology Process of 5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide

There total 3 articles about 5-Amino-1-cyclohexyl-1H-pyrazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 21254-04-6
5-amino-1-cyclohexyl-1H-pyrazol-4-carbonitrile

: 21254-07-9
5-amino-1-cyclohexyl-1H-pyrazol-4-carboxamide

Guidance literature:: With ammonia; water; dihydrogen peroxide; In ethanol; at 20 ℃; for 1h;

Reference yield: 80.7%

: 21254-07-9
5-amino-1-cyclohexyl-1H-pyrazol-4-carboxamide

Guidance literature:: With ammonia; water; dihydrogen peroxide; In ethanol; at 20 ℃; for 18h;

Reference yield:

: 24214-73-1,30929-57-8
cyclohexylhydrazine hydrochloride

: 21254-07-9
5-amino-1-cyclohexyl-1H-pyrazol-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / ethanol / 18 h / 85 °C

2.1: sulfuric acid / 3 h / 0 - 25 °C

2.2: pH 8 - 9

With sulfuric acid; triethylamine; In ethanol;