Tert-butyl 4-(trifluoromethoxy)phenylcarbamate

Base Information

Chemical Name:Tert-butyl 4-(trifluoromethoxy)phenylcarbamate
CAS No.:212696-37-2
Molecular Formula:C12H14F3NO3
Molecular Weight:277.243
Hs Code.:
DSSTox Substance ID:DTXSID10458452
Nikkaji Number:J1.917.924I
Wikidata:Q82281724
Mol file:212696-37-2.mol

Synonyms:TERT-BUTYL 4-(TRIFLUOROMETHOXY)PHENYLCARBAMATE;212696-37-2;Tert-butyl N-[4-(trifluoromethoxy)phenyl]carbamate;tert-Butyl (4-(trifluoromethoxy)phenyl)carbamate;AR2270;SCHEMBL3427239;N-BOC-4-trifluoromethoxyaniline;DTXSID10458452;MFCD09910418;N-Boc para-(trifluoromethoxy)aniline;AKOS014476604;AS-45312;tert-butyl 4-trifluoromethoxyphenylcarbamate;CS-0088075;Tert-butyl-4-(trifluoromethoxy)phenylcarbamate;EN300-157745;TERT-BUTYL4-(TRIFLUOROMETHOXY)PHENYLCARBAMATE;Z1258794338;(4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester;[4-(Trifluoromethoxy)phenyl]carbamic acid tert-butyl ester

Suppliers and Price of Tert-butyl 4-(trifluoromethoxy)phenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
TERT-BUTYL4-(TRIFLUOROMETHOXY)PHENYLCARBAMATE 95
5g
$ 1283.00

Crysdot
Tert-Butyl4-(Trifluoromethoxy)Phenylcarbamate 95+%
5g
$ 776.00

Chemenu
Tert-Butyl4-(Trifluoromethoxy)Phenylcarbamate 95%
5g
$ 733.00

Biosynth Carbosynth
Tert-Butyl 4-(Trifluoromethoxy)Phenylcarbamate
25 mg
$ 77.00

Biosynth Carbosynth
Tert-Butyl 4-(Trifluoromethoxy)Phenylcarbamate
500 mg
$ 485.00

Biosynth Carbosynth
Tert-Butyl 4-(Trifluoromethoxy)Phenylcarbamate
250 mg
$ 302.50

Biosynth Carbosynth
Tert-Butyl 4-(Trifluoromethoxy)Phenylcarbamate
100 mg
$ 242.00

Biosynth Carbosynth
Tert-Butyl 4-(Trifluoromethoxy)Phenylcarbamate
50 mg
$ 151.00

AOBChem
Tert-butyl-4-(trifluoromethoxy)phenylcarbamate 97%
10g
$ 1034.00

American Custom Chemicals Corporation
TERT-BUTYL 4-(TRIFLUOROMETHOXY)PHENYLCARBAMATE 95.00%
1G
$ 1394.66

Total 6 raw suppliers

Chemical Property of Tert-butyl 4-(trifluoromethoxy)phenylcarbamate

Chemical Property:

PSA：47.56000
LogP:4.00520
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:277.09257779
Heavy Atom Count:19
Complexity:304

Purity/Quality:

95% ^*data from raw suppliers

TERT-BUTYL4-(TRIFLUOROMETHOXY)PHENYLCARBAMATE 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC=C(C=C1)OC(F)(F)F

Technology Process of Tert-butyl 4-(trifluoromethoxy)phenylcarbamate

There total 2 articles about Tert-butyl 4-(trifluoromethoxy)phenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 461-82-5
4-(trifluoromethoxy)aniline

: 212696-37-2
tert-butyl N-(4-trifluoromethoxyphenyl)carbamate

Guidance literature:: In toluene; at 100 ℃;
DOI:10.1021/jo0267798

Reference yield: 88.0%

: 865-47-4
potassium tert-butylate

: 35037-73-1
1-isocyanato-4-trifluoromethoxy-benzene

: 212696-37-2
tert-butyl N-(4-trifluoromethoxyphenyl)carbamate

Guidance literature:: potassium tert-butylate; 1-isocyanato-4-trifluoromethoxy-benzene; In tetrahydrofuran; at 0 - 20 ℃;

With ammonium chloride; In tetrahydrofuran; diethyl ether; water;

Reference yield: 86.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 212696-37-2
tert-butyl N-(4-trifluoromethoxyphenyl)carbamate

: 505084-60-6
tert-butyl N-[2-formyl-4-(trifluoromethoxy)phenyl]carbamate

Guidance literature:: tert-butyl N-(4-trifluoromethoxyphenyl)carbamate; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -50 ℃; for 2h;

N,N-dimethyl-formamide; In tetrahydrofuran; pentane; at 25 ℃;
DOI:10.1021/jo0267798