Benzenesulfonyl chloride, 4-(3,5-dimethyl-4-isoxazolyl)-

Base Information

• Chemical Name: Benzenesulfonyl chloride, 4-(3,5-dimethyl-4-isoxazolyl)-
• CAS No.: 2154-81-6
• Molecular Formula: C11H10ClNO3S
• Molecular Weight: 271.72000
• Mol file: 2154-81-6.mol

Synonyms:4-(3,5-Dimethyl-isoxazol-4-yl)-benzenesulfonyl chloride;4-<3,5-Dimethyl-isoxazolyl-(4)>-phenylsulfonylchlorid;

Chemical Property of Benzenesulfonyl chloride, 4-(3,5-dimethyl-4-isoxazolyl)-

Chemical Property:

• PSA: 68.55000
• LogP: 3.96670

Purity/Quality:

99% ^*data from raw suppliers

4-(3,5-dimethyl-4-isoxazolyl)benzenesulfonylchloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenesulfonyl chloride, 4-(3,5-dimethyl-4-isoxazolyl)-

There total 3 articles about Benzenesulfonyl chloride, 4-(3,5-dimethyl-4-isoxazolyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethyl-4-phenyl-isoxazole (4345-46-4) → 4-(3,5-dimethyl-isoxazol-4-yl)-benzenesulfonyl chloride (2154-81-6)

Guidance literature:

With chlorosulfonic acid; In chloroform; Heating;

Reference yield:

3-phenylpentane-2,4-dione (5910-25-8) → 4-(3,5-dimethyl-isoxazol-4-yl)-benzenesulfonyl chloride (2154-81-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₂OH*HCl, Py / ethanol / Heating

2: ClSO₃H / CHCl₃ / Heating

With pyridine; chlorosulfonic acid; hydroxylamine hydrochloride; In ethanol; chloroform;

Reference yield:

3-phenyl-pentane-2,4-dione monooxime (4345-47-5) → 4-(3,5-dimethyl-isoxazol-4-yl)-benzenesulfonyl chloride (2154-81-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HCl / (heating)

2: ClSO₃H / CHCl₃ / Heating

With hydrogenchloride; chlorosulfonic acid; In chloroform;

upstream raw materials:

3,5-dimethyl-4-phenyl-isoxazole

3-phenylpentane-2,4-dione

3-phenyl-pentane-2,4-dione monooxime

Downstream raw materials:

4-(3,5-dimethyl-isoxazol-4-yl)-benzenesulfonamide

7-[4-(3,5-dimethyl-isoxazol-4-yl)-benzenesulfonylamino]-1,2,4,5-tetrahydro-benzo[d]azepine-3-carboxylic acid tert-butyl ester

4-(3,5-dimethyl-isoxazol-4-yl)-N-(2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-benzenesulfonamide

4-(3,5-dimethyl-isoxazol-4-yl)-N-xanthen-9-yl-benzenesulfonamide