S-2-(1,1-diMethylethyl)-1-[(4-Methylphenyl)sulfonyl]-Aziridine

Base Information

Chemical Name:S-2-(1,1-diMethylethyl)-1-[(4-Methylphenyl)sulfonyl]-Aziridine
CAS No.:216220-08-5
Molecular Formula:C13H19NO2S
Molecular Weight:253.365
Hs Code.:
Mol file:216220-08-5.mol

Synonyms:(S)-2-tert-Butyl-1-(toluene-4-sulfonyl)-aziridine;(S)-2-tert-butyl-N-tosylaziridine;(S)-2-(tert-butyl)-1-toluenesulfonylaziridine;(2S)-2-(1,1-dimethylethyl)-1-[(4-methylphenyl)sulfonyl]aziridine;(2S)-2-(1,1-dimethylethyl)-1-[(4-methylphenyl)sulfonyl]-aziridine;

Suppliers and Price of S-2-(1,1-diMethylethyl)-1-[(4-Methylphenyl)sulfonyl]-Aziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of S-2-(1,1-diMethylethyl)-1-[(4-Methylphenyl)sulfonyl]-Aziridine

Chemical Property:

Melting Point:58.5 - 59.2 °C
PSA：45.53000
LogP:3.43270

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S-2-(1,1-diMethylethyl)-1-[(4-Methylphenyl)sulfonyl]-Aziridine

There total 4 articles about S-2-(1,1-diMethylethyl)-1-[(4-Methylphenyl)sulfonyl]-Aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 216220-10-9
(S)-2-(4-methylphenylsulfonylamino)-1-(4-methylsulfonyloxy)-3,3-dimethylbutane

: 216220-08-5
(S)-N-(p-toluenesulfonyl)-2-tert-butylaziridine

Guidance literature:: With potassium hydroxide; water; In benzene; at 20 ℃; for 2h;
DOI:10.1021/ol801259u

Reference yield: 80.0%

: 112245-13-3
(S)-tert-leucinol

: 98-59-9
p-toluenesulfonyl chloride

: 216220-08-5
(S)-N-(p-toluenesulfonyl)-2-tert-butylaziridine

Guidance literature:: (S)-tert-leucinol; p-toluenesulfonyl chloride; With 4 A molecular sieve; triethylamine; In acetonitrile; at 0 - 20 ℃; for 1.33333h;

With dmap; methanesulfonyl chloride; triethylamine; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1016/j.tetlet.2005.11.133

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 216220-08-5
(S)-N-(p-toluenesulfonyl)-2-tert-butylaziridine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine

2: potassium hydroxide / water; benzene / 20 °C

With pyridine; potassium hydroxide; In water; benzene;
DOI:10.1246/bcsj.20110035