15(S)-Methyl-PGE2 methyl ester

Base Information

• Chemical Name: 15(S)-Methyl-PGE2 methyl ester
• CAS No.: 36210-00-1
• Deprecated CAS: 37751-36-3
• Molecular Formula: C22H36O5
• Molecular Weight: 380.5182
• UNII: W62SBA5WFX
• DSSTox Substance ID: DTXSID201117785
• Nikkaji Number: J58.152F
• Mol file: 36210-00-1.mol

Synonyms:15-methylprostaglandin E2 methyl ester;PG(6)E

Chemical Property of 15(S)-Methyl-PGE2 methyl ester

Chemical Property:

• Vapor Pressure: 4.31E-12mmHg at 25°C
• Boiling Point: 500°Cat760mmHg
• Flash Point: 162.3°C
• Density: 1.092g/cm³
• Storage Temp.: −20°C
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 13
• Exact Mass: 380.25627424
• Heavy Atom Count: 27
• Complexity: 525

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-20/21/22-36/37/38-43
• Safety Statements: 16-26-36-43-36/37-33-25-9

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC(C)(C=CC1C(CC(=O)C1CC=CCCCC(=O)OC)O)O
• Isomeric SMILES: CCCCC[C@@](C)(/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)OC)O)O

Technology Process of 15(S)-Methyl-PGE2 methyl ester

There total 5 articles about 15(S)-Methyl-PGE2 methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (15S)-15-Methyl-PGE2-methylester (36210-00-1,39219-61-9,53317-76-3,53317-77-4,53317-78-5,53317-79-6,62446-67-7,104012-10-4)

Guidance literature:

aus Keton (17S);

DOI:10.1021/ja00825a027

Reference yield:

→ 15-methyl-8β,12α,15β-prostaglandin-E2-methylester (36210-00-1,39219-61-9,53317-76-3,53317-77-4,53317-78-5,53317-79-6,62446-67-7,104012-10-4)

Guidance literature:

15-methyl-8β,12α,15β-PGA2-10,11-epoxide-methylester (XLVIII), aluminium amalgam, diethylether, methanol;

Reference yield:

→ 15-methyl-8β,11β,12α-prostaglandin-E2-methylester (36210-00-1,39219-61-9,53317-76-3,53317-77-4,53317-78-5,53317-79-6,62446-67-7,104012-10-4)

Guidance literature:

15-methyl-8β,9β,11β,12α-PGF2-methylester, 1) N-trimethylsilyldiethylamine (-> 11-trimethylsilylether), Collins reag. (-> 15-methyl-8β,11β,12α-PGE2-methylester-11-trimethylsilylether), 2) acetic acid, H2O;

Refernces

• 1、 Yankee,Bundy. "(15S)-15-methylprostaglandins.". . p. 3651 - 3652. Retrieved 2007/10/16.