5-(4-CHLOROPHENYL)-6H-1,3,4-THIADIAZIN-2-AMINIUM BROMIDE

Base Information

• Chemical Name: 5-(4-CHLOROPHENYL)-6H-1,3,4-THIADIAZIN-2-AMINIUM BROMIDE
• CAS No.: 219657-90-6
• Molecular Formula: C9H8ClN3S.BrH
• Molecular Weight: 306.61000
• Mol file: 219657-90-6.mol

Synonyms:

Chemical Property of 5-(4-CHLOROPHENYL)-6H-1,3,4-THIADIAZIN-2-AMINIUM BROMIDE

Chemical Property:

• PSA: 76.04000
• LogP: 2.63520

Purity/Quality:

5-(4-Chlorophenyl)-6H-1,3,4-thiadiazin-2-aminium bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4-CHLOROPHENYL)-6H-1,3,4-THIADIAZIN-2-AMINIUM BROMIDE

There total 3 articles about 5-(4-CHLOROPHENYL)-6H-1,3,4-THIADIAZIN-2-AMINIUM BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

thiosemicarbazide (79-19-6) + 4-chlorobenzoylmethyl bromide (536-38-9) → 2-amino-5-(4-chlorophenyl)-6H-1,3,4-thiadiazine hydrobromide (219657-90-6)

Guidance literature:

Reference yield:

C9H10ClN3OS*BrH → 2-amino-5-(4-chlorophenyl)-6H-1,3,4-thiadiazine hydrobromide (219657-90-6)

Guidance literature:

With 48percent aq. HBr; In ethanol; for 0.5h; Heating;

DOI:10.1021/jm010887p

Reference yield:

4-chlorobenzoylmethyl bromide (536-38-9) → 2-amino-5-(4-chlorophenyl)-6H-1,3,4-thiadiazine hydrobromide (219657-90-6)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 0 - 20 °C

2: 48percent aq. HBr / ethanol / 0.5 h / Heating

With 48percent aq. HBr; In ethanol;

DOI:10.1021/jm010887p

upstream raw materials:

thiosemicarbazide

4-chlorobenzoylmethyl bromide