1-(4-CHLOROBENZYL)-1H-INDOLE-2-CARBOXYLIC ACID

Base Information

Chemical Name:1-(4-CHLOROBENZYL)-1H-INDOLE-2-CARBOXYLIC ACID
CAS No.:220677-67-8
Molecular Formula:C16H12ClNO2
Molecular Weight:285.73
Hs Code.:
Mol file:220677-67-8.mol

Synonyms:1-(4-Chlorobenzyl)-1H-indole-2-carboxylic acid;1-(4-Chloro-benzyl)-1H-indole-2-carboxylic acid;N-(4-Chlorobenzyl)indole-2-carboxylic acid;

Suppliers and Price of 1-(4-CHLOROBENZYL)-1H-INDOLE-2-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(4-Chlorobenzyl)-1H-indole-2-carboxylic acid
500mg
$ 184.00

Crysdot
1-(4-Chlorobenzyl)-1H-indole-2-carboxylicacid 97%
5g
$ 582.00

Chemenu
1-(4-Chlorobenzyl)-1H-indole-2-carboxylicacid 95%+
5g
$ 550.00

A1 Biochem Labs
1-(4-Chlorobenzyl)-1H-indole-2-carboxylicacid 95%
5 g
$ 950.00

Total 3 raw suppliers

Chemical Property of 1-(4-CHLOROBENZYL)-1H-INDOLE-2-CARBOXYLIC ACID

Chemical Property:

Melting Point:198 - 202 °C
PSA：42.23000
LogP:4.04120

Purity/Quality:

98%min ^*data from raw suppliers

1-(4-Chlorobenzyl)-1H-indole-2-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:

Useful:

Technology Process of 1-(4-CHLOROBENZYL)-1H-INDOLE-2-CARBOXYLIC ACID

There total 9 articles about 1-(4-CHLOROBENZYL)-1H-INDOLE-2-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 199604-34-7
ethyl 1-(4-chlorobenzyl)-1H-indole-2-carboxylate

: 220677-67-8
1-(4-chlorobenzyl)-1H-indole-2-carboxylic Acid

Guidance literature:: With potassium hydroxide; In ethanol; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2016.08.044

Reference yield: 85.0%

: 220677-67-8
1-(4-chlorobenzyl)-1H-indole-2-carboxylic Acid

Guidance literature:

Reference yield:

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 220677-67-8
1-(4-chlorobenzyl)-1H-indole-2-carboxylic Acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 1 h / 80 °C

2: aq. LiOH / tetrahydrofuran / 2 h / 60 °C

With lithium hydroxide; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.06.020