Tuftsin

Base Information

Chemical Name:Tuftsin
CAS No.:112592-90-2
Molecular Formula:C21H40N8O6
Molecular Weight:0
Hs Code.:
Wikipedia:Tuftsin
Metabolomics Workbench ID:38746
Mol file:112592-90-2.mol

Synonyms:L-Thr-L-Lys-L-Pro-L-Arg;L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine;Taftsin;Tuftsin

Suppliers and Price of Tuftsin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Tuftsin

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：0.00000
Density:1.48g/cm³
LogP:0.00000
XLogP3:-7
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:15
Exact Mass:500.30708103
Heavy Atom Count:35
Complexity:760

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)O)N)O
Isomeric SMILES:C[C@H]([C@@H](C(=O)NC(CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N)O

Technology Process of Tuftsin

There total 16 articles about Tuftsin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 78432-02-7
Benzyloxycarbonylthreonyl(ε-tert-butoxycarbonyllysyl)prolylarginine

: 9063-57-4,112592-90-2
thr-Lys-Pro-Arg

Guidance literature:: With hydrogen bromide; In trifluoroacetic acid; for 0.333333h;
DOI:10.1007/BF00765712

Reference yield: 59.0%

: 154509-00-9
Boc-Thr(OBn)-Lys(2Cl,Z)-Pro-Arg(Tos)-OBn

: 9063-57-4,112592-90-2
thr-Lys-Pro-Arg

Guidance literature:: With Ethyl methyl sulfide; methyl-phenyl-thioether; methoxybenzene; In trifluoroacetic acid; for 1h;
DOI:10.1016/S0040-4020(01)81544-1

Reference yield:

: 29388-63-4
H-Arg(Tos)-OBzl

: 9063-57-4,112592-90-2
thr-Lys-Pro-Arg

Guidance literature:: Multi-step reaction with 6 steps

1: DCC / HOBt / dimethylformamide / 0 °C

2: 2.) NaHCO₃ / 1.) TFA, room temp., 1.5 hrs; 2.) water, dichloromethane, room temp, 0.5 hr

3: DCC / HOBt / dimethylformamide / 0 °C

4: 2.) NaHCO₃ / 1.) TFA, room temp., 1.5 hrs; 2.) water, dichloromethane, room temp, 0.5 hr

5: DCC / HOBt / dimethylformamide / 0 °C

6: 59 percent / anisole, ethyl methyl sulfide, thioanisole / trifluoroacetic acid / 1 h

With Ethyl methyl sulfide; methyl-phenyl-thioether; sodium hydrogencarbonate; methoxybenzene; dicyclohexyl-carbodiimide; benzotriazol-1-ol; In N,N-dimethyl-formamide; trifluoroacetic acid;
DOI:10.1016/S0040-4020(01)81544-1