2-oxo-6-phenyl-4-(trifluoromethyl)-1H-pyridine-3-carboxamide

Base Information

Chemical Name:2-oxo-6-phenyl-4-(trifluoromethyl)-1H-pyridine-3-carboxamide
CAS No.:22122-95-8
Molecular Formula:C₁₃H₉F₃N₂O₂
Molecular Weight:282.222
Hs Code.:
DSSTox Substance ID:DTXSID50446196
Wikidata:Q82264789

Synonyms:CTK0I8776;22122-95-8;DTXSID50446196;3-aminocarbonyl-4-trifluoromethyl-6 phenyl-2(1h)-pyridone

Suppliers and Price of 2-oxo-6-phenyl-4-(trifluoromethyl)-1H-pyridine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-oxo-6-phenyl-4-(trifluoromethyl)-1H-pyridine-3-carboxamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:282.06161202
Heavy Atom Count:20
Complexity:500

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=C(C(=O)N2)C(=O)N)C(F)(F)F

Technology Process of 2-oxo-6-phenyl-4-(trifluoromethyl)-1H-pyridine-3-carboxamide

There total 1 articles about 2-oxo-6-phenyl-4-(trifluoromethyl)-1H-pyridine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22122-95-8
3-aminocarbonyl-4-trifluoromethyl-7-phenyl-2(1H)-pyridone

Guidance literature:: 3-Cyan-6-phenyl-4-trifluormethyl-1H-pyridon-(2), konz. H2SO4;

Reference yield: 65.2%

: 22122-95-8
3-aminocarbonyl-4-trifluoromethyl-7-phenyl-2(1H)-pyridone

: 7-trifluoromethyl-5-phenyl-2-oxo-(1H)-oxazolo[5,4-b]pyridine potassium salt

Guidance literature:: With potassium hydroxide; potassium hypobromite; for 1h; Ambient temperature;
DOI:10.1007/BF01165915

Reference yield:

: 22122-95-8
3-aminocarbonyl-4-trifluoromethyl-7-phenyl-2(1H)-pyridone

: 179996-84-0
1-Methyl-5-phenyl-7-trifluoromethyl-1H-oxazolo[5,4-b]pyridin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 65.2 percent / potassium hypobromite, aq. KOH / 1 h / Ambient temperature

2: 92.8 percent / dimethylformamide / 1 h / Heating

With potassium hydroxide; potassium hypobromite; In N,N-dimethyl-formamide;
DOI:10.1007/BF01165915